Analysis of Disease Free Survival and Overall Survival of HER2 Positive Subtype Breast Cancer Patients at Prof. Dr. I.G.N.G. Ngoerah Denpasar Hospital
Aim: This study aim to assess the characteristics of the patients, as well as the 3-year and 5-year overall survival and disease free survival of HER2+ breast cancer patients treated at Prof. Dr. I.G.N.G. Ngoerah Hospital Denpasar Methods: This retrospective cohort study assessed survival rates and...
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| Format: | Article |
| Language: | English |
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Universitas Udayana
2025-02-01
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| Series: | JBN (Jurnal Bedah Nasional) |
| Online Access: | https://ojs.unud.ac.id/index.php/jbn/article/view/120383 |
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| author | Gde Ary Putra Kamajaya Ni Gusti Ayu Agung Manik Yuniawaty Wetan I Gede Budhi Setiawan |
| author_facet | Gde Ary Putra Kamajaya Ni Gusti Ayu Agung Manik Yuniawaty Wetan I Gede Budhi Setiawan |
| author_sort | Gde Ary Putra Kamajaya |
| collection | DOAJ |
| description | Aim: This study aim to assess the characteristics of the patients, as well as the 3-year and 5-year overall survival and disease free survival of HER2+ breast cancer patients treated at Prof. Dr. I.G.N.G. Ngoerah Hospital Denpasar Methods: This retrospective cohort study assessed survival rates and prognostic factors among HER2+ breast cancer patients treated at Prof. Dr. I.G.N.G. Ngoerah Hospital Denpasar from January 2017 to December 2022. The study used medical records to examine variables such as age, tumor characteristics, metastasis patterns, histology, treatments, and survival outcomes over 3- and 5-year periods. Results: The 3-year survival rate was 77.7% and the 5-year survival rate was 74.3%, with median survival times of 31 months (95%CI 30.7-32.86) and 49 months (95%CI 47.85-52.089), respectively. Disease-free survival rates indicated median durations of 33 months (95%CI 32.949-34.545) at 3 years and 54 months (95% CI 53.063-56.357) at 5 years. Conclusion: This study enhances understanding of HER2+ breast cancer prognosis, emphasizing the critical roles of lymph node status, metastatic burden, and treatment strategies in determining patient outcomes. |
| format | Article |
| id | doaj-art-57da5ffc5acc4576b3e1b31c078764dc |
| institution | DOAJ |
| issn | 2548-5962 2548-981X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Universitas Udayana |
| record_format | Article |
| series | JBN (Jurnal Bedah Nasional) |
| spelling | doaj-art-57da5ffc5acc4576b3e1b31c078764dc2025-08-20T03:11:15ZengUniversitas UdayanaJBN (Jurnal Bedah Nasional)2548-59622548-981X2025-02-01911710.24843/JBN.2025.v09.i01.p01120383Analysis of Disease Free Survival and Overall Survival of HER2 Positive Subtype Breast Cancer Patients at Prof. Dr. I.G.N.G. Ngoerah Denpasar HospitalGde Ary Putra Kamajaya0Ni Gusti Ayu Agung Manik Yuniawaty Wetan1I Gede Budhi Setiawan2General Surgery Training Program, Medical Faculty of Udayana University/Prof. Dr. I.G.N.G Ngoerah General Hospital, Denpasar, Bali, Indonesia.2 Surgical Oncology Division, Department of Surgery, Medical Faculty of Udayana University/Prof. Dr. I.G.N.G Ngoerah General Hospital, Denpasar, Bali, Indonesia.2 Surgical Oncology Division, Department of Surgery, Medical Faculty of Udayana University/Prof. Dr. I.G.N.G Ngoerah General Hospital, Denpasar, Bali, Indonesia.Aim: This study aim to assess the characteristics of the patients, as well as the 3-year and 5-year overall survival and disease free survival of HER2+ breast cancer patients treated at Prof. Dr. I.G.N.G. Ngoerah Hospital Denpasar Methods: This retrospective cohort study assessed survival rates and prognostic factors among HER2+ breast cancer patients treated at Prof. Dr. I.G.N.G. Ngoerah Hospital Denpasar from January 2017 to December 2022. The study used medical records to examine variables such as age, tumor characteristics, metastasis patterns, histology, treatments, and survival outcomes over 3- and 5-year periods. Results: The 3-year survival rate was 77.7% and the 5-year survival rate was 74.3%, with median survival times of 31 months (95%CI 30.7-32.86) and 49 months (95%CI 47.85-52.089), respectively. Disease-free survival rates indicated median durations of 33 months (95%CI 32.949-34.545) at 3 years and 54 months (95% CI 53.063-56.357) at 5 years. Conclusion: This study enhances understanding of HER2+ breast cancer prognosis, emphasizing the critical roles of lymph node status, metastatic burden, and treatment strategies in determining patient outcomes.https://ojs.unud.ac.id/index.php/jbn/article/view/120383 |
| spellingShingle | Gde Ary Putra Kamajaya Ni Gusti Ayu Agung Manik Yuniawaty Wetan I Gede Budhi Setiawan Analysis of Disease Free Survival and Overall Survival of HER2 Positive Subtype Breast Cancer Patients at Prof. Dr. I.G.N.G. Ngoerah Denpasar Hospital JBN (Jurnal Bedah Nasional) |
| title | Analysis of Disease Free Survival and Overall Survival of HER2 Positive Subtype Breast Cancer Patients at Prof. Dr. I.G.N.G. Ngoerah Denpasar Hospital |
| title_full | Analysis of Disease Free Survival and Overall Survival of HER2 Positive Subtype Breast Cancer Patients at Prof. Dr. I.G.N.G. Ngoerah Denpasar Hospital |
| title_fullStr | Analysis of Disease Free Survival and Overall Survival of HER2 Positive Subtype Breast Cancer Patients at Prof. Dr. I.G.N.G. Ngoerah Denpasar Hospital |
| title_full_unstemmed | Analysis of Disease Free Survival and Overall Survival of HER2 Positive Subtype Breast Cancer Patients at Prof. Dr. I.G.N.G. Ngoerah Denpasar Hospital |
| title_short | Analysis of Disease Free Survival and Overall Survival of HER2 Positive Subtype Breast Cancer Patients at Prof. Dr. I.G.N.G. Ngoerah Denpasar Hospital |
| title_sort | analysis of disease free survival and overall survival of her2 positive subtype breast cancer patients at prof dr i g n g ngoerah denpasar hospital |
| url | https://ojs.unud.ac.id/index.php/jbn/article/view/120383 |
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