Peptide-Based Treatment: A Promising Cancer Therapy
Many new therapies are currently being used to treat cancer. Among these new methods, chemotherapy based on peptides has been of great interest due to the unique advantages of peptides, such as a low molecular weight, the ability to specifically target tumor cells, and low toxicity in normal tissues...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2015/761820 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850223860957315072 |
|---|---|
| author | Yu-Feng Xiao Meng-Meng Jie Bo-Sheng Li Chang-Jiang Hu Rui Xie Bo Tang Shi-Ming Yang |
| author_facet | Yu-Feng Xiao Meng-Meng Jie Bo-Sheng Li Chang-Jiang Hu Rui Xie Bo Tang Shi-Ming Yang |
| author_sort | Yu-Feng Xiao |
| collection | DOAJ |
| description | Many new therapies are currently being used to treat cancer. Among these new methods, chemotherapy based on peptides has been of great interest due to the unique advantages of peptides, such as a low molecular weight, the ability to specifically target tumor cells, and low toxicity in normal tissues. In treating cancer, peptide-based chemotherapy can be mainly divided into three types, peptide-alone therapy, peptide vaccines, and peptide-conjugated nanomaterials. Peptide-alone therapy may specifically enhance the immune system’s response to kill tumor cells. Peptide-based vaccines have been used in advanced cancers to improve patients’ overall survival. Additionally, the combination of peptides with nanomaterials expands the therapeutic ability of peptides to treat cancer by enhancing drug delivery and sensitivity. In this review, we mainly focus on the new advances in the application of peptides in treating cancer in recent years, including diagnosis, treatment, and prognosis. |
| format | Article |
| id | doaj-art-57d5e2ecc8f344e3ac7271db48967b50 |
| institution | OA Journals |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-57d5e2ecc8f344e3ac7271db48967b502025-08-20T02:05:48ZengWileyJournal of Immunology Research2314-88612314-71562015-01-01201510.1155/2015/761820761820Peptide-Based Treatment: A Promising Cancer TherapyYu-Feng Xiao0Meng-Meng Jie1Bo-Sheng Li2Chang-Jiang Hu3Rui Xie4Bo Tang5Shi-Ming Yang6Department of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, ChinaDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, ChinaDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, ChinaDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, ChinaDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, ChinaDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, ChinaDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, ChinaMany new therapies are currently being used to treat cancer. Among these new methods, chemotherapy based on peptides has been of great interest due to the unique advantages of peptides, such as a low molecular weight, the ability to specifically target tumor cells, and low toxicity in normal tissues. In treating cancer, peptide-based chemotherapy can be mainly divided into three types, peptide-alone therapy, peptide vaccines, and peptide-conjugated nanomaterials. Peptide-alone therapy may specifically enhance the immune system’s response to kill tumor cells. Peptide-based vaccines have been used in advanced cancers to improve patients’ overall survival. Additionally, the combination of peptides with nanomaterials expands the therapeutic ability of peptides to treat cancer by enhancing drug delivery and sensitivity. In this review, we mainly focus on the new advances in the application of peptides in treating cancer in recent years, including diagnosis, treatment, and prognosis.http://dx.doi.org/10.1155/2015/761820 |
| spellingShingle | Yu-Feng Xiao Meng-Meng Jie Bo-Sheng Li Chang-Jiang Hu Rui Xie Bo Tang Shi-Ming Yang Peptide-Based Treatment: A Promising Cancer Therapy Journal of Immunology Research |
| title | Peptide-Based Treatment: A Promising Cancer Therapy |
| title_full | Peptide-Based Treatment: A Promising Cancer Therapy |
| title_fullStr | Peptide-Based Treatment: A Promising Cancer Therapy |
| title_full_unstemmed | Peptide-Based Treatment: A Promising Cancer Therapy |
| title_short | Peptide-Based Treatment: A Promising Cancer Therapy |
| title_sort | peptide based treatment a promising cancer therapy |
| url | http://dx.doi.org/10.1155/2015/761820 |
| work_keys_str_mv | AT yufengxiao peptidebasedtreatmentapromisingcancertherapy AT mengmengjie peptidebasedtreatmentapromisingcancertherapy AT boshengli peptidebasedtreatmentapromisingcancertherapy AT changjianghu peptidebasedtreatmentapromisingcancertherapy AT ruixie peptidebasedtreatmentapromisingcancertherapy AT botang peptidebasedtreatmentapromisingcancertherapy AT shimingyang peptidebasedtreatmentapromisingcancertherapy |