Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson’s disease

Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson’s disease

Learning dexterous motor sequences is crucial to autonomy and quality of life but can be altered in Parkinson’s disease (PD). Learning involves optimizing pre-movement planning (preplanning) of multiple sequence elements to reduce computational overhead during active movement. However, it is unclear...

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Bibliographic Details
Main Authors: Kara N. Presbrey, Thomas A. Wozny, Kenneth H. Louie, Simon Little, Philip A. Starr, Reza Abbasi-Asl, Doris D. Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Neuroscience
Subjects:
Parkinson’s disease
movement decoding
functional connectivity
sequencing
motor learning
motor planning
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1542493/full
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