Milk profiles of selenoamino acids, selenoenzymes, and selenoproteins of peripartal dairy cows fed with different selenium sources
Objective This study aimed to investigate the effect of dietary nanoselenium (nanoSe) and sodium selenite (SS) on the concentrations of selenoamino acids, the activities of selenoenzymes, and the mRNA expressions of selenoproteins in the milk of peripartal dairy cows. Methods Three diets included a...
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Asian-Australasian Association of Animal Production Societies
2025-06-01
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| Series: | Animal Bioscience |
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| Online Access: | http://www.animbiosci.org/upload/pdf/ab-24-0571.pdf |
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| author | Xiaoyu Ji Xuejuan Deng Ning Liu Jianping Wang |
| author_facet | Xiaoyu Ji Xuejuan Deng Ning Liu Jianping Wang |
| author_sort | Xiaoyu Ji |
| collection | DOAJ |
| description | Objective This study aimed to investigate the effect of dietary nanoselenium (nanoSe) and sodium selenite (SS) on the concentrations of selenoamino acids, the activities of selenoenzymes, and the mRNA expressions of selenoproteins in the milk of peripartal dairy cows. Methods Three diets included a control (basal diet) with background selenium at 0.06 mg/kg and treatments with either SS or nanoSe added at the same selenium concentration of 1.00 mg/kg of diet. A total of 45 dairy cows were randomly allocated to three groups. The feeding trial lasted for 42 days from prenatal 21 days to postnatal 21 days. Results NanoSe increased (p<0.05) milk yield compared to the control and SS. In milk, both SS and nanoSe increased (p<0.05) the concentrations of selenium, selenocysteine, and selenomethionine, and the activities of glutathione peroxidase 4, glutathione reductase, thioredoxin reductase, glutathione S-transferase, and iodothyronine deiodinases (type 2 and 3). The nanoSe showed higher (p<0.05) effects on these parameters than SS. Also, dietary nanoSe upregulated (p<0.05) the mRNA expressions of selenoproteins P, W, S, F, M, N, K, O, H, and I in milk compared to the control. For most selenoproteins, there was no difference between SS and nanoSe, only selenoprotein K was higher (p<0.05) in nanoSe than in SS. Conclusion In conclusion, dietary nanoSe increased milk yield, milk selenoamino acids and selenoproteins in peripartal dairy cows. |
| format | Article |
| id | doaj-art-57b2c58ade344fa6a2e8cf4df7fa64bf |
| institution | OA Journals |
| issn | 2765-0189 2765-0235 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Asian-Australasian Association of Animal Production Societies |
| record_format | Article |
| series | Animal Bioscience |
| spelling | doaj-art-57b2c58ade344fa6a2e8cf4df7fa64bf2025-08-20T02:28:19ZengAsian-Australasian Association of Animal Production SocietiesAnimal Bioscience2765-01892765-02352025-06-013861175118110.5713/ab.24.057125404Milk profiles of selenoamino acids, selenoenzymes, and selenoproteins of peripartal dairy cows fed with different selenium sourcesXiaoyu Ji0Xuejuan Deng1Ning Liu2Jianping Wang3 Department of Animal Science, Henan University of Science and Technology, Luoyang, China Department of Research and Development, National Engineering Research Center of Biological Feed, Beijing, China Department of Animal Science, Henan University of Science and Technology, Luoyang, China Department of Animal Science, Henan University of Science and Technology, Luoyang, ChinaObjective This study aimed to investigate the effect of dietary nanoselenium (nanoSe) and sodium selenite (SS) on the concentrations of selenoamino acids, the activities of selenoenzymes, and the mRNA expressions of selenoproteins in the milk of peripartal dairy cows. Methods Three diets included a control (basal diet) with background selenium at 0.06 mg/kg and treatments with either SS or nanoSe added at the same selenium concentration of 1.00 mg/kg of diet. A total of 45 dairy cows were randomly allocated to three groups. The feeding trial lasted for 42 days from prenatal 21 days to postnatal 21 days. Results NanoSe increased (p<0.05) milk yield compared to the control and SS. In milk, both SS and nanoSe increased (p<0.05) the concentrations of selenium, selenocysteine, and selenomethionine, and the activities of glutathione peroxidase 4, glutathione reductase, thioredoxin reductase, glutathione S-transferase, and iodothyronine deiodinases (type 2 and 3). The nanoSe showed higher (p<0.05) effects on these parameters than SS. Also, dietary nanoSe upregulated (p<0.05) the mRNA expressions of selenoproteins P, W, S, F, M, N, K, O, H, and I in milk compared to the control. For most selenoproteins, there was no difference between SS and nanoSe, only selenoprotein K was higher (p<0.05) in nanoSe than in SS. Conclusion In conclusion, dietary nanoSe increased milk yield, milk selenoamino acids and selenoproteins in peripartal dairy cows.http://www.animbiosci.org/upload/pdf/ab-24-0571.pdfdairy cowsnanoseleniumselenoamino acidsselenoenzymesselenoproteins |
| spellingShingle | Xiaoyu Ji Xuejuan Deng Ning Liu Jianping Wang Milk profiles of selenoamino acids, selenoenzymes, and selenoproteins of peripartal dairy cows fed with different selenium sources Animal Bioscience dairy cows nanoselenium selenoamino acids selenoenzymes selenoproteins |
| title | Milk profiles of selenoamino acids, selenoenzymes, and selenoproteins of peripartal dairy cows fed with different selenium sources |
| title_full | Milk profiles of selenoamino acids, selenoenzymes, and selenoproteins of peripartal dairy cows fed with different selenium sources |
| title_fullStr | Milk profiles of selenoamino acids, selenoenzymes, and selenoproteins of peripartal dairy cows fed with different selenium sources |
| title_full_unstemmed | Milk profiles of selenoamino acids, selenoenzymes, and selenoproteins of peripartal dairy cows fed with different selenium sources |
| title_short | Milk profiles of selenoamino acids, selenoenzymes, and selenoproteins of peripartal dairy cows fed with different selenium sources |
| title_sort | milk profiles of selenoamino acids selenoenzymes and selenoproteins of peripartal dairy cows fed with different selenium sources |
| topic | dairy cows nanoselenium selenoamino acids selenoenzymes selenoproteins |
| url | http://www.animbiosci.org/upload/pdf/ab-24-0571.pdf |
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