Recent progress on acoustofluidic manipulation of cells and particles

Acoustofluidics, an interdisciplinary nexus of microfluidics and acoustics, is propelling the critical functionalities of manipulation, separation, and mixing within microscale environments. This integration leverages the accuracy of microfluidics with the manipulation capabilities of acoustics, the...

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Main Authors: Wang Zeyu, Xia Jianping, Garry Ryan, Weitz David A., Li Xiangming
Format: Article
Language:English
Published: Science Press 2024-03-01
Series:National Science Open
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Online Access:https://www.sciengine.com/doi/10.1360/nso/20230080
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author Wang Zeyu
Xia Jianping
Garry Ryan
Weitz David A.
Li Xiangming
author_facet Wang Zeyu
Xia Jianping
Garry Ryan
Weitz David A.
Li Xiangming
author_sort Wang Zeyu
collection DOAJ
description Acoustofluidics, an interdisciplinary nexus of microfluidics and acoustics, is propelling the critical functionalities of manipulation, separation, and mixing within microscale environments. This integration leverages the accuracy of microfluidics with the manipulation capabilities of acoustics, thereby enhancing the vital sample processing steps and satisfying inquiries in experiments. To fulfill the requisites of practical application in clinical and research arenas, the evolution of acoustofluidics concentrates on accomplishing finer particle separation, instantaneous manipulation, and augmented integration capacity. Acoustofluidics has evolved into a sophisticated and versatile instrument for handling specimens and reactants, prompting a trend towards devices characterized by stable performance at elevated frequencies, programmable control, and seamless integration with auxiliary microfluidic systems. In this review, we present the latest advancements in the development of sophisticated acoustofluidic systems that enhance efficiency and enable precise modulation of performance across spatial and temporal scales, thereby extending their functionality and suitability for practical applications.
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spelling doaj-art-57ac1467ea804bb6b7207b9e3aa72a282025-08-20T02:06:27ZengScience PressNational Science Open2097-11682024-03-01410.1360/nso/20230080eb33e642Recent progress on acoustofluidic manipulation of cells and particlesWang Zeyu0Xia Jianping1Garry Ryan2Weitz David A.3Li Xiangming4["Frontier Institute of Science and Technology (FIST), Xi’an Jiaotong University, Xi’an 710049, China"]["Pratt School of Engineering, Duke University, Durham, NC 27705, USA"]["School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA"]["School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA"]["Frontier Institute of Science and Technology (FIST), Xi’an Jiaotong University, Xi’an 710049, China","Micro- and Nano-technology Research Center, State Key Laboratory for Manufacturing Systems Engineering, Xi’an Jiaotong University, Xi’an 710049, China"]Acoustofluidics, an interdisciplinary nexus of microfluidics and acoustics, is propelling the critical functionalities of manipulation, separation, and mixing within microscale environments. This integration leverages the accuracy of microfluidics with the manipulation capabilities of acoustics, thereby enhancing the vital sample processing steps and satisfying inquiries in experiments. To fulfill the requisites of practical application in clinical and research arenas, the evolution of acoustofluidics concentrates on accomplishing finer particle separation, instantaneous manipulation, and augmented integration capacity. Acoustofluidics has evolved into a sophisticated and versatile instrument for handling specimens and reactants, prompting a trend towards devices characterized by stable performance at elevated frequencies, programmable control, and seamless integration with auxiliary microfluidic systems. In this review, we present the latest advancements in the development of sophisticated acoustofluidic systems that enhance efficiency and enable precise modulation of performance across spatial and temporal scales, thereby extending their functionality and suitability for practical applications.https://www.sciengine.com/doi/10.1360/nso/20230080acoustofluidicsmicrofabricationacousticsmicrofluidics
spellingShingle Wang Zeyu
Xia Jianping
Garry Ryan
Weitz David A.
Li Xiangming
Recent progress on acoustofluidic manipulation of cells and particles
National Science Open
acoustofluidics
microfabrication
acoustics
microfluidics
title Recent progress on acoustofluidic manipulation of cells and particles
title_full Recent progress on acoustofluidic manipulation of cells and particles
title_fullStr Recent progress on acoustofluidic manipulation of cells and particles
title_full_unstemmed Recent progress on acoustofluidic manipulation of cells and particles
title_short Recent progress on acoustofluidic manipulation of cells and particles
title_sort recent progress on acoustofluidic manipulation of cells and particles
topic acoustofluidics
microfabrication
acoustics
microfluidics
url https://www.sciengine.com/doi/10.1360/nso/20230080
work_keys_str_mv AT wangzeyu recentprogressonacoustofluidicmanipulationofcellsandparticles
AT xiajianping recentprogressonacoustofluidicmanipulationofcellsandparticles
AT garryryan recentprogressonacoustofluidicmanipulationofcellsandparticles
AT weitzdavida recentprogressonacoustofluidicmanipulationofcellsandparticles
AT lixiangming recentprogressonacoustofluidicmanipulationofcellsandparticles