The role of dendritic cells in COVID-19 infection
The persistent pandemic of coronavirus disease in 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently poses a major infectious threat to public health around the world. COVID-19 is an infectious disease characterized by strong induction of inflammatory cy...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Emerging Microbes and Infections |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2023.2195019 |
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| author | Xuying Wang Fei Guan Heather Miller Maria G Byazrova Fabio Candotti Kamel Benlagha Niels Olsen Saraiva Camara Jiahui Lei Alexander Filatov Chaohong Liu |
| author_facet | Xuying Wang Fei Guan Heather Miller Maria G Byazrova Fabio Candotti Kamel Benlagha Niels Olsen Saraiva Camara Jiahui Lei Alexander Filatov Chaohong Liu |
| author_sort | Xuying Wang |
| collection | DOAJ |
| description | The persistent pandemic of coronavirus disease in 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently poses a major infectious threat to public health around the world. COVID-19 is an infectious disease characterized by strong induction of inflammatory cytokines, progressive lung inflammation, and potential multiple organs dysfunction. SARS-CoV-2 infection is closely related to the innate immune system and adaptive immune system. Dendritic cells (DCs), as a “bridge” connecting innate immunity and adaptive immunity, play many important roles in viral diseases. In this review, we will pay special attention to the possible mechanism of dendritic cells in human viral transmission and clinical progression of diseases, as well as the reduction and dysfunction of DCs in severe SARS-CoV-2 infection, so as to understand the mechanism and immunological characteristics of SARS-CoV-2 infection. |
| format | Article |
| id | doaj-art-579bbf1ae07a4c12ad89ac9e8ac86347 |
| institution | Kabale University |
| issn | 2222-1751 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-579bbf1ae07a4c12ad89ac9e8ac863472025-08-20T03:52:56ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512023-12-0112110.1080/22221751.2023.2195019The role of dendritic cells in COVID-19 infectionXuying Wang0Fei Guan1Heather Miller2Maria G Byazrova3Fabio Candotti4Kamel Benlagha5Niels Olsen Saraiva Camara6Jiahui Lei7Alexander Filatov8Chaohong Liu9Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science Technology, Wuhan, People’s Republic of ChinaDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science Technology, Wuhan, People’s Republic of ChinaCytek Biosciences, R&D Clinical Reagents, Fremont, CA, USALaboratory of Immunochemistry, National Research Center Institute of Immunology, Federal Medical Biological Agency of Russia, Moscow, RussiaDivision of Immunology and Allergy, Lausanne University Hospital and University of Lausanne, Lausanne, SwitzerlandInstitut de Recherche Saint-Louis, Université de Paris, Paris, FranceLaboratory of Human Immunology, Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, BrazilDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science Technology, Wuhan, People’s Republic of ChinaLaboratory of Immunochemistry, National Research Center Institute of Immunology, Federal Medical Biological Agency of Russia, Moscow, RussiaDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science Technology, Wuhan, People’s Republic of ChinaThe persistent pandemic of coronavirus disease in 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently poses a major infectious threat to public health around the world. COVID-19 is an infectious disease characterized by strong induction of inflammatory cytokines, progressive lung inflammation, and potential multiple organs dysfunction. SARS-CoV-2 infection is closely related to the innate immune system and adaptive immune system. Dendritic cells (DCs), as a “bridge” connecting innate immunity and adaptive immunity, play many important roles in viral diseases. In this review, we will pay special attention to the possible mechanism of dendritic cells in human viral transmission and clinical progression of diseases, as well as the reduction and dysfunction of DCs in severe SARS-CoV-2 infection, so as to understand the mechanism and immunological characteristics of SARS-CoV-2 infection.https://www.tandfonline.com/doi/10.1080/22221751.2023.2195019SARS-CoV-2COVID-19dendritic cellimmunopathologyviral infection |
| spellingShingle | Xuying Wang Fei Guan Heather Miller Maria G Byazrova Fabio Candotti Kamel Benlagha Niels Olsen Saraiva Camara Jiahui Lei Alexander Filatov Chaohong Liu The role of dendritic cells in COVID-19 infection Emerging Microbes and Infections SARS-CoV-2 COVID-19 dendritic cell immunopathology viral infection |
| title | The role of dendritic cells in COVID-19 infection |
| title_full | The role of dendritic cells in COVID-19 infection |
| title_fullStr | The role of dendritic cells in COVID-19 infection |
| title_full_unstemmed | The role of dendritic cells in COVID-19 infection |
| title_short | The role of dendritic cells in COVID-19 infection |
| title_sort | role of dendritic cells in covid 19 infection |
| topic | SARS-CoV-2 COVID-19 dendritic cell immunopathology viral infection |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2023.2195019 |
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