Analytic markovian rates for generalized protein structure evolution.
A general understanding of the complex phenomenon of protein evolution requires the accurate description of the constraints that define the sub-space of proteins with mutations that do not appreciably reduce the fitness of the organism. Such constraints can have multiple origins, in this work we pre...
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| Main Authors: | Ivan Coluzza, James T MacDonald, Michael I Sadowski, William R Taylor, Richard A Goldstein |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0034228&type=printable |
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