Risk prediction in acute coronary syndrome depending on the types of myocard revascularization
Risk of complications in patients with acute coronary syndrome determination has received much attention and offered a variety of options for scales in the last years. GRACE scale is the most informative method to assess the risk of death during hospitalization period and during the next 6 months at...
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Zaporizhzhia State Medical and Pharmaceutical University
2016-12-01
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| Series: | Zaporožskij Medicinskij Žurnal |
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| Online Access: | http://zmj.zsmu.edu.ua/article/view/85485/83143 |
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| author | R. V. Denina |
| author_facet | R. V. Denina |
| author_sort | R. V. Denina |
| collection | DOAJ |
| description | Risk of complications in patients with acute coronary syndrome determination has received much attention and offered a variety of options for scales in the last years. GRACE scale is the most informative method to assess the risk of death during hospitalization period and during the next 6 months at present. Some studies recommend to complement GRACE scale with detection of the N-terminal prohormone brain natriuretic peptide (NT-proBNP) blood levels.
The purpose of the study was to assess risk factors by GRACE scale and activity in serum levels of NT–proBNP in myocardial infarction depending on the types of coronary arteries revascularization.
Materials and Methods. The study involved 80 patients with acute myocardial infarction with heart failure; the average age of patients was (61.16±5.79) years, 52 (65 %) men. The patients were divided into 4 groups. Group I included patients who were prescribed thrombolytic therapy (n=10); group II patients underwent percutaneous coronary intervention (PCI) with stenting of the infarction–depending vessels (n=35); group III involved patients (n=23) who were administered both methods of treatment. Group IV included 12 individuals who were administered conservative treatment.
Results. The research showed that the lowest levels of NT–proBNP were observed on the 7th day in patients who have been administered percutaneous coronary intervention (PCI) with stenting of the infarction–depending vessels (254.1±11.3 fmol/ml, p<0.05). The risk of adverse events evaluated by the GRACE scale in patients with MI after performed PCI with stenting of the infarction–depending vessels and thrombolytic therapy is lower (12.2±1.35 %) than in patients who were administered thrombolytic therapy (14.23±0.58 %) and those with conservative treatment (15.63±0.89 %).
Conclusion. The risk of death by GRACE scale in patients with myocardial infarction after performed PCI with stenting of the infarction–depending vessels and thrombolytic therapy is lower than in patients without coronary intervention. |
| format | Article |
| id | doaj-art-578b0d6ca6364804b2ce22cf4b0eb264 |
| institution | OA Journals |
| issn | 2306-4145 2310-1210 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | Zaporizhzhia State Medical and Pharmaceutical University |
| record_format | Article |
| series | Zaporožskij Medicinskij Žurnal |
| spelling | doaj-art-578b0d6ca6364804b2ce22cf4b0eb2642025-08-20T01:57:08ZengZaporizhzhia State Medical and Pharmaceutical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102016-12-0161720http://dx.doi.org/10.14739/2310-1210.2016.6.85485Risk prediction in acute coronary syndrome depending on the types of myocard revascularizationR. V. DeninaRisk of complications in patients with acute coronary syndrome determination has received much attention and offered a variety of options for scales in the last years. GRACE scale is the most informative method to assess the risk of death during hospitalization period and during the next 6 months at present. Some studies recommend to complement GRACE scale with detection of the N-terminal prohormone brain natriuretic peptide (NT-proBNP) blood levels. The purpose of the study was to assess risk factors by GRACE scale and activity in serum levels of NT–proBNP in myocardial infarction depending on the types of coronary arteries revascularization. Materials and Methods. The study involved 80 patients with acute myocardial infarction with heart failure; the average age of patients was (61.16±5.79) years, 52 (65 %) men. The patients were divided into 4 groups. Group I included patients who were prescribed thrombolytic therapy (n=10); group II patients underwent percutaneous coronary intervention (PCI) with stenting of the infarction–depending vessels (n=35); group III involved patients (n=23) who were administered both methods of treatment. Group IV included 12 individuals who were administered conservative treatment. Results. The research showed that the lowest levels of NT–proBNP were observed on the 7th day in patients who have been administered percutaneous coronary intervention (PCI) with stenting of the infarction–depending vessels (254.1±11.3 fmol/ml, p<0.05). The risk of adverse events evaluated by the GRACE scale in patients with MI after performed PCI with stenting of the infarction–depending vessels and thrombolytic therapy is lower (12.2±1.35 %) than in patients who were administered thrombolytic therapy (14.23±0.58 %) and those with conservative treatment (15.63±0.89 %). Conclusion. The risk of death by GRACE scale in patients with myocardial infarction after performed PCI with stenting of the infarction–depending vessels and thrombolytic therapy is lower than in patients without coronary intervention.http://zmj.zsmu.edu.ua/article/view/85485/83143PrognosisMyocardial InfarctionRevascularizationNT–proBNPGRACE |
| spellingShingle | R. V. Denina Risk prediction in acute coronary syndrome depending on the types of myocard revascularization Zaporožskij Medicinskij Žurnal Prognosis Myocardial Infarction Revascularization NT–proBNP GRACE |
| title | Risk prediction in acute coronary syndrome depending on the types of myocard revascularization |
| title_full | Risk prediction in acute coronary syndrome depending on the types of myocard revascularization |
| title_fullStr | Risk prediction in acute coronary syndrome depending on the types of myocard revascularization |
| title_full_unstemmed | Risk prediction in acute coronary syndrome depending on the types of myocard revascularization |
| title_short | Risk prediction in acute coronary syndrome depending on the types of myocard revascularization |
| title_sort | risk prediction in acute coronary syndrome depending on the types of myocard revascularization |
| topic | Prognosis Myocardial Infarction Revascularization NT–proBNP GRACE |
| url | http://zmj.zsmu.edu.ua/article/view/85485/83143 |
| work_keys_str_mv | AT rvdenina riskpredictioninacutecoronarysyndromedependingonthetypesofmyocardrevascularization |