Antibiotic use for digestive system diseases (ICD-10: K00-K93) at an Indonesian government teaching hospital in 2021
Background: Digestive system diseases pose a significant global health challenge. In many developing countries, inappropriate antibiotic use is common, and the COVID-19 pandemic further disrupted standard antibiotic prescribing practices. This study evaluated antibiotic prescribing patterns for dige...
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Society of Gastrointestinal Intervention
2025-04-01
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| Series: | International Journal of Gastrointestinal Intervention |
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| Online Access: | https://www.ijgii.org/journal/view.html?doi=10.18528/ijgii240083 |
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| author | Rahmah Inasiyyah Ikhwan Yuda Kusuma Fauziah Fauziah Fiqih Nurkholis Khamdiyah Indah Kurniasih |
| author_facet | Rahmah Inasiyyah Ikhwan Yuda Kusuma Fauziah Fauziah Fiqih Nurkholis Khamdiyah Indah Kurniasih |
| author_sort | Rahmah Inasiyyah |
| collection | DOAJ |
| description | Background: Digestive system diseases pose a significant global health challenge. In many developing countries, inappropriate antibiotic use is common, and the COVID-19 pandemic further disrupted standard antibiotic prescribing practices. This study evaluated antibiotic prescribing patterns for digestive system diseases in a major Indonesian hospital during 2021. Methods: We conducted a retrospective, observational analysis of antibiotic prescriptions for 47,698 inpatients with digestive system diseases at Cilacap Government Teaching Hospital, Indonesia, throughout 2021. Data were extracted from electronic medical records and analyzed based on patient demographics, International Classification of Diseases, 10th revision classifications, World Health Organization Access, Watch, and Reserve categories, and routes of administration. Statistical analyses and visualizations were performed using Microsoft Excel (Microsoft) and R Studio (Posit). Results: Among 2,183 patients diagnosed with digestive system diseases, the majority were active adults, with a predominance of male patients. The most frequently prescribed antibiotics belonged to the “Watch” group. Acute appendicitis (n = 416), inguinal hernia (n = 250), and functional dyspepsia (n = 169) were the leading diagnoses. Antibiotic administration was more prevalent among females for these conditions, despite higher overall antibiotic use for digestive system diseases among males. Cases peaked at 319 in December and dropped to 65 in July. The dry season months recorded fewer cases (July: 65, August: 129). The most prescribed antibiotics were ceftriaxone (n = 638), metronidazole (n = 486), and cefazolin (n = 216), indicating a predominant use of broad-spectrum agents. Conclusion: The study reveals a high reliance on broad-spectrum antibiotics, particularly those in the “Watch” group, suggesting potential overuse. These findings underscore the need for improved antibiotic stewardship practices, especially in regions facing the compounded challenges of the COVID-19 pandemic. |
| format | Article |
| id | doaj-art-5782a973a2584a57b6bb87cc863233b2 |
| institution | DOAJ |
| issn | 2636-0004 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Society of Gastrointestinal Intervention |
| record_format | Article |
| series | International Journal of Gastrointestinal Intervention |
| spelling | doaj-art-5782a973a2584a57b6bb87cc863233b22025-08-20T02:55:48ZengSociety of Gastrointestinal InterventionInternational Journal of Gastrointestinal Intervention2636-00042025-04-01142647010.18528/ijgii240083ijgii240083Antibiotic use for digestive system diseases (ICD-10: K00-K93) at an Indonesian government teaching hospital in 2021Rahmah Inasiyyah0Ikhwan Yuda Kusuma1Fauziah Fauziah2Fiqih Nurkholis3Khamdiyah Indah Kurniasih4Pharmacy Study Program, Faculty of Health, Universitas Harapan Bangsa, Purwokerto, IndonesiaPharmacy Study Program, Faculty of Health, Universitas Harapan Bangsa, Purwokerto, IndonesiaPharmacy Study Program, Faculty of Health, Universitas Harapan Bangsa, Purwokerto, IndonesiaPharmacy Study Program, Faculty of Health, Universitas Harapan Bangsa, Purwokerto, IndonesiaPharmacy Study Program, Faculty of Health, Universitas Harapan Bangsa, Purwokerto, IndonesiaBackground: Digestive system diseases pose a significant global health challenge. In many developing countries, inappropriate antibiotic use is common, and the COVID-19 pandemic further disrupted standard antibiotic prescribing practices. This study evaluated antibiotic prescribing patterns for digestive system diseases in a major Indonesian hospital during 2021. Methods: We conducted a retrospective, observational analysis of antibiotic prescriptions for 47,698 inpatients with digestive system diseases at Cilacap Government Teaching Hospital, Indonesia, throughout 2021. Data were extracted from electronic medical records and analyzed based on patient demographics, International Classification of Diseases, 10th revision classifications, World Health Organization Access, Watch, and Reserve categories, and routes of administration. Statistical analyses and visualizations were performed using Microsoft Excel (Microsoft) and R Studio (Posit). Results: Among 2,183 patients diagnosed with digestive system diseases, the majority were active adults, with a predominance of male patients. The most frequently prescribed antibiotics belonged to the “Watch” group. Acute appendicitis (n = 416), inguinal hernia (n = 250), and functional dyspepsia (n = 169) were the leading diagnoses. Antibiotic administration was more prevalent among females for these conditions, despite higher overall antibiotic use for digestive system diseases among males. Cases peaked at 319 in December and dropped to 65 in July. The dry season months recorded fewer cases (July: 65, August: 129). The most prescribed antibiotics were ceftriaxone (n = 638), metronidazole (n = 486), and cefazolin (n = 216), indicating a predominant use of broad-spectrum agents. Conclusion: The study reveals a high reliance on broad-spectrum antibiotics, particularly those in the “Watch” group, suggesting potential overuse. These findings underscore the need for improved antibiotic stewardship practices, especially in regions facing the compounded challenges of the COVID-19 pandemic.https://www.ijgii.org/journal/view.html?doi=10.18528/ijgii240083anti-bacterial agents; covid-19; digestive system diseases; drug utilization |
| spellingShingle | Rahmah Inasiyyah Ikhwan Yuda Kusuma Fauziah Fauziah Fiqih Nurkholis Khamdiyah Indah Kurniasih Antibiotic use for digestive system diseases (ICD-10: K00-K93) at an Indonesian government teaching hospital in 2021 International Journal of Gastrointestinal Intervention anti-bacterial agents; covid-19; digestive system diseases; drug utilization |
| title | Antibiotic use for digestive system diseases (ICD-10: K00-K93) at an Indonesian government teaching hospital in 2021 |
| title_full | Antibiotic use for digestive system diseases (ICD-10: K00-K93) at an Indonesian government teaching hospital in 2021 |
| title_fullStr | Antibiotic use for digestive system diseases (ICD-10: K00-K93) at an Indonesian government teaching hospital in 2021 |
| title_full_unstemmed | Antibiotic use for digestive system diseases (ICD-10: K00-K93) at an Indonesian government teaching hospital in 2021 |
| title_short | Antibiotic use for digestive system diseases (ICD-10: K00-K93) at an Indonesian government teaching hospital in 2021 |
| title_sort | antibiotic use for digestive system diseases icd 10 k00 k93 at an indonesian government teaching hospital in 2021 |
| topic | anti-bacterial agents; covid-19; digestive system diseases; drug utilization |
| url | https://www.ijgii.org/journal/view.html?doi=10.18528/ijgii240083 |
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