Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population
Metabolic syndrome (MS) amplifies hypertension (HTN) associated with increased risk of cardiovascular disease (CVD). MS components and other CVD risk measures were investigated in different stages of hypertension. 534 apparently healthy Nigerian traders aged 18–105 years were participants of a cohor...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2013/351357 |
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| author | M. A. Charles-Davies A. A. Fasanmade J. A. Olaniyi O. E. Oyewole M. O. Owolabi J. R. Adebusuyi O. Hassan M. T. Ajobo M. O. Ebesunun K. Adigun K. S. Akinlade U. A. Fabian O. O. Popoola S. K. Rahamon W. Okunbolade M. A. Ogunlakin O. G. Arinola E. O Agbedana |
| author_facet | M. A. Charles-Davies A. A. Fasanmade J. A. Olaniyi O. E. Oyewole M. O. Owolabi J. R. Adebusuyi O. Hassan M. T. Ajobo M. O. Ebesunun K. Adigun K. S. Akinlade U. A. Fabian O. O. Popoola S. K. Rahamon W. Okunbolade M. A. Ogunlakin O. G. Arinola E. O Agbedana |
| author_sort | M. A. Charles-Davies |
| collection | DOAJ |
| description | Metabolic syndrome (MS) amplifies hypertension (HTN) associated with increased risk of cardiovascular disease (CVD). MS components and other CVD risk measures were investigated in different stages of hypertension. 534 apparently healthy Nigerian traders aged 18–105 years were participants of a cohort study. The International Diabetes Federation (2005) and the National High Blood Pressure Education Program Coordinating Committee criteria were used for MS and HTN classifications, respectively. Anthropometric indices were obtained by standard methods. Levels of fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), and high-density lipoprotein cholesterol (HDLC) were determined by enzymatic methods, while low-density lipoprotein cholesterol (LDLC) was calculated. Data analysed statistically were significant at P<0.05. 143 (26.8%), 197 (36.9%), and 194 (36.3%) of the traders had normotension, pre-HTN and HTN (stages 1 and 2), respectively. All indices tested except HDLC were significantly different among BP groups (P<0.05). Waist to hip (WHR) and waist to height (WHT) ratios were significantly different between HTN groups (P<0.05). HTN was associated with MS and female gender (P<0.05). Metabolic alterations and significant HTN were observed. Treatment of the individual components of the syndrome and improvement of modifiable metabolic factors may be necessary to reduce MS and high BP. |
| format | Article |
| id | doaj-art-577e99c8282747b2a1afc69b3be74d20 |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-577e99c8282747b2a1afc69b3be74d202025-02-03T01:09:50ZengWileyInternational Journal of Hypertension2090-03842090-03922013-01-01201310.1155/2013/351357351357Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian PopulationM. A. Charles-Davies0A. A. Fasanmade1J. A. Olaniyi2O. E. Oyewole3M. O. Owolabi4J. R. Adebusuyi5O. Hassan6M. T. Ajobo7M. O. Ebesunun8K. Adigun9K. S. Akinlade10U. A. Fabian11O. O. Popoola12S. K. Rahamon13W. Okunbolade14M. A. Ogunlakin15O. G. Arinola16E. O Agbedana17Department of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Haematology, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Health Promotion and Education, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaMedical Social Services Department, University College Hospital, Ibadan 200212, NigeriaMedical Social Services Department, University College Hospital, Ibadan 200212, NigeriaDietetics Department, University College Hospital, Ibadan 200212, NigeriaDepartment of Chemical Pathology, College of Health Sciences, Olabisi Onabanjo University, Ago-Iwoye 120005, NigeriaGeneral Out Patient Unit, University College Hospital, Ibadan 200212, NigeriaDepartment of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaDepartment of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan 200284, NigeriaMetabolic syndrome (MS) amplifies hypertension (HTN) associated with increased risk of cardiovascular disease (CVD). MS components and other CVD risk measures were investigated in different stages of hypertension. 534 apparently healthy Nigerian traders aged 18–105 years were participants of a cohort study. The International Diabetes Federation (2005) and the National High Blood Pressure Education Program Coordinating Committee criteria were used for MS and HTN classifications, respectively. Anthropometric indices were obtained by standard methods. Levels of fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), and high-density lipoprotein cholesterol (HDLC) were determined by enzymatic methods, while low-density lipoprotein cholesterol (LDLC) was calculated. Data analysed statistically were significant at P<0.05. 143 (26.8%), 197 (36.9%), and 194 (36.3%) of the traders had normotension, pre-HTN and HTN (stages 1 and 2), respectively. All indices tested except HDLC were significantly different among BP groups (P<0.05). Waist to hip (WHR) and waist to height (WHT) ratios were significantly different between HTN groups (P<0.05). HTN was associated with MS and female gender (P<0.05). Metabolic alterations and significant HTN were observed. Treatment of the individual components of the syndrome and improvement of modifiable metabolic factors may be necessary to reduce MS and high BP.http://dx.doi.org/10.1155/2013/351357 |
| spellingShingle | M. A. Charles-Davies A. A. Fasanmade J. A. Olaniyi O. E. Oyewole M. O. Owolabi J. R. Adebusuyi O. Hassan M. T. Ajobo M. O. Ebesunun K. Adigun K. S. Akinlade U. A. Fabian O. O. Popoola S. K. Rahamon W. Okunbolade M. A. Ogunlakin O. G. Arinola E. O Agbedana Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population International Journal of Hypertension |
| title | Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population |
| title_full | Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population |
| title_fullStr | Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population |
| title_full_unstemmed | Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population |
| title_short | Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population |
| title_sort | metabolic alterations in different stages of hypertension in an apparently healthy nigerian population |
| url | http://dx.doi.org/10.1155/2013/351357 |
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