A Fatal Case of Wernicke’s Encephalopathy after Sleeve Gastrectomy for Morbid Obesity

Wernicke’s encephalopathy is an acute neuropsychiatric disorder, due to thiamine (vitamin B1) deficiency. It is traditionally described in chronic alcohol abusers; however obesity surgery is an emerging cause, as the number of bariatric procedures increases. A high index of clinical suspicion is req...

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Main Authors: Dimitrios K. Manatakis, Nikolaos Georgopoulos
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2014/281210
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author Dimitrios K. Manatakis
Nikolaos Georgopoulos
author_facet Dimitrios K. Manatakis
Nikolaos Georgopoulos
author_sort Dimitrios K. Manatakis
collection DOAJ
description Wernicke’s encephalopathy is an acute neuropsychiatric disorder, due to thiamine (vitamin B1) deficiency. It is traditionally described in chronic alcohol abusers; however obesity surgery is an emerging cause, as the number of bariatric procedures increases. A high index of clinical suspicion is required, since initial symptoms may be nonspecific and the classic triad of ophthalmoplegia, gait and stance disorders, and mental confusion is present only in one-third of patients. Laboratory tests can be within normal range and typical MRI brain lesions are found only in 50% of cases. Aggressive supplementation with intravenous thiamine should not be delayed until confirmation of diagnosis, as it may fully reverse symptoms, but almost half the patients will still display permanent neurological deficit. We present our experience with a fatal case of Wernicke’s encephalopathy, following laparoscopic sleeve gastrectomy for morbid obesity.
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spelling doaj-art-577b6fa9c84c4201aadab5d5b9f8f3482025-02-03T06:13:47ZengWileyCase Reports in Surgery2090-69002090-69192014-01-01201410.1155/2014/281210281210A Fatal Case of Wernicke’s Encephalopathy after Sleeve Gastrectomy for Morbid ObesityDimitrios K. Manatakis0Nikolaos Georgopoulos12nd Surgical Department, Athens Naval and Veterans Hospital, 70 Deinokratous Street, Athens, Greece2nd Surgical Department, Athens Naval and Veterans Hospital, 70 Deinokratous Street, Athens, GreeceWernicke’s encephalopathy is an acute neuropsychiatric disorder, due to thiamine (vitamin B1) deficiency. It is traditionally described in chronic alcohol abusers; however obesity surgery is an emerging cause, as the number of bariatric procedures increases. A high index of clinical suspicion is required, since initial symptoms may be nonspecific and the classic triad of ophthalmoplegia, gait and stance disorders, and mental confusion is present only in one-third of patients. Laboratory tests can be within normal range and typical MRI brain lesions are found only in 50% of cases. Aggressive supplementation with intravenous thiamine should not be delayed until confirmation of diagnosis, as it may fully reverse symptoms, but almost half the patients will still display permanent neurological deficit. We present our experience with a fatal case of Wernicke’s encephalopathy, following laparoscopic sleeve gastrectomy for morbid obesity.http://dx.doi.org/10.1155/2014/281210
spellingShingle Dimitrios K. Manatakis
Nikolaos Georgopoulos
A Fatal Case of Wernicke’s Encephalopathy after Sleeve Gastrectomy for Morbid Obesity
Case Reports in Surgery
title A Fatal Case of Wernicke’s Encephalopathy after Sleeve Gastrectomy for Morbid Obesity
title_full A Fatal Case of Wernicke’s Encephalopathy after Sleeve Gastrectomy for Morbid Obesity
title_fullStr A Fatal Case of Wernicke’s Encephalopathy after Sleeve Gastrectomy for Morbid Obesity
title_full_unstemmed A Fatal Case of Wernicke’s Encephalopathy after Sleeve Gastrectomy for Morbid Obesity
title_short A Fatal Case of Wernicke’s Encephalopathy after Sleeve Gastrectomy for Morbid Obesity
title_sort fatal case of wernicke s encephalopathy after sleeve gastrectomy for morbid obesity
url http://dx.doi.org/10.1155/2014/281210
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AT nikolaosgeorgopoulos afatalcaseofwernickesencephalopathyaftersleevegastrectomyformorbidobesity
AT dimitrioskmanatakis fatalcaseofwernickesencephalopathyaftersleevegastrectomyformorbidobesity
AT nikolaosgeorgopoulos fatalcaseofwernickesencephalopathyaftersleevegastrectomyformorbidobesity