Primary hepatic epithelioid hemangioendothelioma: a case report

Epithelioid hemangioendothelioma is a low-grade malignant tumor of vascular origin. The rarity of hepatic epithelioid hemangioendothelioma (HEHE) makes the diagnosis and treatment of this entity challenging. We report a case of a 69-year-old female patient who suffered from HEHE and complained of ab...

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Main Authors: Jing-Rui Wang, Qi-Jun Yang, Bei Lu, Yang Cai, Jun-Jie Yin
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605241306649
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author Jing-Rui Wang
Qi-Jun Yang
Bei Lu
Yang Cai
Jun-Jie Yin
author_facet Jing-Rui Wang
Qi-Jun Yang
Bei Lu
Yang Cai
Jun-Jie Yin
author_sort Jing-Rui Wang
collection DOAJ
description Epithelioid hemangioendothelioma is a low-grade malignant tumor of vascular origin. The rarity of hepatic epithelioid hemangioendothelioma (HEHE) makes the diagnosis and treatment of this entity challenging. We report a case of a 69-year-old female patient who suffered from HEHE and complained of abdominal distension pain with dizziness and appetite loss for more than half a month. Enhanced computed tomography of the upper abdomen indicated multiple space-occupying lesions in the liver. The pathological results of color ultrasound puncture suggested HEHE. We performed transcatheter arterial chemoembolization and relevant examinations according to the patient’s condition and their choice. We followed the patient for 5 years and found that she developed recurrent intrahepatic metastasis of the tumor. Computed tomography was performed again after 3 months of treatment with anlotinib and the tumor did not show any progression. HEHE is a relatively rare hepatic malignant tumor derived from vascular endothelial cells, with a low incidence, atypical clinical manifestations, and a difficult diagnosis that can only be confirmed with pathological results. Currently, appropriate treatment methods should be selected according to the specific conditions of the patient.
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series Journal of International Medical Research
spelling doaj-art-577a1a6f1afd40e89774b10412b8fab12024-12-28T11:03:30ZengSAGE PublishingJournal of International Medical Research1473-23002024-12-015210.1177/03000605241306649Primary hepatic epithelioid hemangioendothelioma: a case reportJing-Rui WangQi-Jun YangBei LuYang CaiJun-Jie YinEpithelioid hemangioendothelioma is a low-grade malignant tumor of vascular origin. The rarity of hepatic epithelioid hemangioendothelioma (HEHE) makes the diagnosis and treatment of this entity challenging. We report a case of a 69-year-old female patient who suffered from HEHE and complained of abdominal distension pain with dizziness and appetite loss for more than half a month. Enhanced computed tomography of the upper abdomen indicated multiple space-occupying lesions in the liver. The pathological results of color ultrasound puncture suggested HEHE. We performed transcatheter arterial chemoembolization and relevant examinations according to the patient’s condition and their choice. We followed the patient for 5 years and found that she developed recurrent intrahepatic metastasis of the tumor. Computed tomography was performed again after 3 months of treatment with anlotinib and the tumor did not show any progression. HEHE is a relatively rare hepatic malignant tumor derived from vascular endothelial cells, with a low incidence, atypical clinical manifestations, and a difficult diagnosis that can only be confirmed with pathological results. Currently, appropriate treatment methods should be selected according to the specific conditions of the patient.https://doi.org/10.1177/03000605241306649
spellingShingle Jing-Rui Wang
Qi-Jun Yang
Bei Lu
Yang Cai
Jun-Jie Yin
Primary hepatic epithelioid hemangioendothelioma: a case report
Journal of International Medical Research
title Primary hepatic epithelioid hemangioendothelioma: a case report
title_full Primary hepatic epithelioid hemangioendothelioma: a case report
title_fullStr Primary hepatic epithelioid hemangioendothelioma: a case report
title_full_unstemmed Primary hepatic epithelioid hemangioendothelioma: a case report
title_short Primary hepatic epithelioid hemangioendothelioma: a case report
title_sort primary hepatic epithelioid hemangioendothelioma a case report
url https://doi.org/10.1177/03000605241306649
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AT yangcai primaryhepaticepithelioidhemangioendotheliomaacasereport
AT junjieyin primaryhepaticepithelioidhemangioendotheliomaacasereport