Severity of atopic dermatitis is associated with gut-derived metabolites and leaky gut-related biomarkers

Severity of atopic dermatitis is associated with gut-derived metabolites and leaky gut-related biomarkers

Abstract Dysbiosis of the gut microbiota may contribute to metabolic dysregulation, intestinal barrier disruption, and inflammatory disorders. The objective was to identify gut-derived metabolites and leaky gut biomarkers linked to atopic dermatitis. Fifty adult patients with atopic dermatitis and 2...

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Main Authors: Leszek Blicharz, Emilia Samborowska, Radosław Zagożdżon, Iwona Bukowska-Ośko, Joanna Czuwara, Michał Zych, Aleksander Roszczyk, Karol Perlejewski, Karolina Makowska, Joanna Nowaczyk, Michał Zaremba, Karolina Kazimierska, Anna Waśkiel-Burnat, Michał Dadlez, Zbigniew Samochocki, Małgorzata Olszewska, Marek Radkowski, Lidia Rudnicka
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Atopic dermatitis
Biomarker
Diet
Gut-skin axis
Leaky gut
Metabolite
Online Access:https://doi.org/10.1038/s41598-025-09520-y
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