Design and simulation of a highly sensitive photonic crystal fiber sensor for malaria detection
This research focuses on developing an innovative optical sensor utilizing photonic crystal fiber with a unique cladding structure. The photonic crystal fiber’s cladding consists of four layers of circular air holes, with two of them filled with hemoglobin. This arrangement renders the photonic crys...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Results in Optics |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666950124001408 |
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| author | Ilhem Mired Hicham Chikh-Bled Mohammed Debbal |
| author_facet | Ilhem Mired Hicham Chikh-Bled Mohammed Debbal |
| author_sort | Ilhem Mired |
| collection | DOAJ |
| description | This research focuses on developing an innovative optical sensor utilizing photonic crystal fiber with a unique cladding structure. The photonic crystal fiber’s cladding consists of four layers of circular air holes, with two of them filled with hemoglobin. This arrangement renders the photonic crystal fiber sensitive to changes in hemoglobin concentration, primarily investigating its impact on chromatic dispersion – the wavelength-dependent refractive index variation. The study analyzes two specific wavelengths, 1.2 µm and 1.4 µm, finding high sensitivity at 1.2 µm, calculated to be 0.232 ps/(nm·km)/(g/L). The potential application lies in malaria diagnosis through non-invasive blood sample analysis. We selected the refractive index of an infected red blood cell at the ring stage, setting it at n = 1.395. Our proposed sensor demonstrates outstanding performance in diagnosing malaria at an HGB concentration of 38 g/L at 1.2 µm and at an HGB concentration of 40 g/L at 1.4 µm. By monitoring hemoglobin concentration changes, this photonic crystal fiber-based sensor offers a promising method for early and accurate malaria detection, thus potentially improving global healthcare. |
| format | Article |
| id | doaj-art-577381a7e34844c8bbb0ced502973126 |
| institution | OA Journals |
| issn | 2666-9501 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Optics |
| spelling | doaj-art-577381a7e34844c8bbb0ced5029731262025-08-20T01:54:53ZengElsevierResults in Optics2666-95012024-12-011710074310.1016/j.rio.2024.100743Design and simulation of a highly sensitive photonic crystal fiber sensor for malaria detectionIlhem Mired0Hicham Chikh-Bled1Mohammed Debbal2Smart Structure Laboratory (SSL), University of Ain Temouchent, 46000 Ain-Temouchent, AlgeriaTelecommunications Laboratory of Tlemcen (LTT), University of Abou-Bekr BELKAID, 13000 Tlemcen, AlgeriaTelecommunications Laboratory of Tlemcen (LTT), Tlemcen 13000, University of Ain Temouchent, 46000 Ain-Temouchent, Algeria; Corresponding author.This research focuses on developing an innovative optical sensor utilizing photonic crystal fiber with a unique cladding structure. The photonic crystal fiber’s cladding consists of four layers of circular air holes, with two of them filled with hemoglobin. This arrangement renders the photonic crystal fiber sensitive to changes in hemoglobin concentration, primarily investigating its impact on chromatic dispersion – the wavelength-dependent refractive index variation. The study analyzes two specific wavelengths, 1.2 µm and 1.4 µm, finding high sensitivity at 1.2 µm, calculated to be 0.232 ps/(nm·km)/(g/L). The potential application lies in malaria diagnosis through non-invasive blood sample analysis. We selected the refractive index of an infected red blood cell at the ring stage, setting it at n = 1.395. Our proposed sensor demonstrates outstanding performance in diagnosing malaria at an HGB concentration of 38 g/L at 1.2 µm and at an HGB concentration of 40 g/L at 1.4 µm. By monitoring hemoglobin concentration changes, this photonic crystal fiber-based sensor offers a promising method for early and accurate malaria detection, thus potentially improving global healthcare.http://www.sciencedirect.com/science/article/pii/S2666950124001408Photonic Crystal FiberOptical SensorChromatic DispersionSensitivityRefractive IndexHemoglobin |
| spellingShingle | Ilhem Mired Hicham Chikh-Bled Mohammed Debbal Design and simulation of a highly sensitive photonic crystal fiber sensor for malaria detection Results in Optics Photonic Crystal Fiber Optical Sensor Chromatic Dispersion Sensitivity Refractive Index Hemoglobin |
| title | Design and simulation of a highly sensitive photonic crystal fiber sensor for malaria detection |
| title_full | Design and simulation of a highly sensitive photonic crystal fiber sensor for malaria detection |
| title_fullStr | Design and simulation of a highly sensitive photonic crystal fiber sensor for malaria detection |
| title_full_unstemmed | Design and simulation of a highly sensitive photonic crystal fiber sensor for malaria detection |
| title_short | Design and simulation of a highly sensitive photonic crystal fiber sensor for malaria detection |
| title_sort | design and simulation of a highly sensitive photonic crystal fiber sensor for malaria detection |
| topic | Photonic Crystal Fiber Optical Sensor Chromatic Dispersion Sensitivity Refractive Index Hemoglobin |
| url | http://www.sciencedirect.com/science/article/pii/S2666950124001408 |
| work_keys_str_mv | AT ilhemmired designandsimulationofahighlysensitivephotoniccrystalfibersensorformalariadetection AT hichamchikhbled designandsimulationofahighlysensitivephotoniccrystalfibersensorformalariadetection AT mohammeddebbal designandsimulationofahighlysensitivephotoniccrystalfibersensorformalariadetection |