Small Molecules in the Treatment of Acute Severe Ulcerative Colitis: A Review of Current Evidence

Small Molecules in the Treatment of Acute Severe Ulcerative Colitis: A Review of Current Evidence

Ulcerative colitis (UC) is an inflammatory bowel disease in which one-quarter of patients are at risk of developing a severe form of the disease known as acute severe UC (ASUC). This condition exposes patients to serious complications, including toxic megacolon, surgical intervention, and even death...

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Bibliographic Details
Main Authors: Raffaele Pellegrino, Giuseppe Imperio, Ilaria De Costanzo, Michele Izzo, Fabio Landa, Assunta Tambaro, Antonietta Gerarda Gravina, Alessandro Federico
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
acute severe ulcerative colitis
ulcerative colitis
small molecules
tofacitinib
upadacitinib
filgotinib
Online Access:https://www.mdpi.com/1424-8247/18/3/308
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