Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges

Androgen Insensitivity Syndrome (AIS) and its heterogeneous phenotypes comprise the pieces of a challenging clinical problem. The lack of standardized guidelines results in controversies regarding the proper diagnostic and therapeutic approach, including the time and type of intervention. Due to its...

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Main Authors: Filippa Pritsini, Georgios A. Kanakis, Ioannis Kyrgios, Eleni P. Kotanidou, Eleni Litou, Konstantina Mouzaki, Aggeliki Kleisarchaki, Dimitrios G. Goulis, Assimina Galli-Tsinopoulou
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2017/8313162
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author Filippa Pritsini
Georgios A. Kanakis
Ioannis Kyrgios
Eleni P. Kotanidou
Eleni Litou
Konstantina Mouzaki
Aggeliki Kleisarchaki
Dimitrios G. Goulis
Assimina Galli-Tsinopoulou
author_facet Filippa Pritsini
Georgios A. Kanakis
Ioannis Kyrgios
Eleni P. Kotanidou
Eleni Litou
Konstantina Mouzaki
Aggeliki Kleisarchaki
Dimitrios G. Goulis
Assimina Galli-Tsinopoulou
author_sort Filippa Pritsini
collection DOAJ
description Androgen Insensitivity Syndrome (AIS) and its heterogeneous phenotypes comprise the pieces of a challenging clinical problem. The lack of standardized guidelines results in controversies regarding the proper diagnostic and therapeutic approach, including the time and type of intervention. Due to its variable phenotype, AIS is not diagnosed at the proper age that would allow optimal psychological and medical support to the patient. Therapeutic approaches are not established, mainly due to the rarity of the disease. In addition, various social and ethical consequences may emerge. The aim of this double case report is to outline the difficulties that may rise during diagnostic, therapeutic, and psychological approach of AIS, especially concerning the handling of the relatives’ reaction.
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language English
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publisher Wiley
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series Case Reports in Endocrinology
spelling doaj-art-576cbeda0068494b8cb580f85f2eacbf2025-02-03T01:11:46ZengWileyCase Reports in Endocrinology2090-65012090-651X2017-01-01201710.1155/2017/83131628313162Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical ChallengesFilippa Pritsini0Georgios A. Kanakis1Ioannis Kyrgios2Eleni P. Kotanidou3Eleni Litou4Konstantina Mouzaki5Aggeliki Kleisarchaki6Dimitrios G. Goulis7Assimina Galli-Tsinopoulou8Unit of Pediatric Endocrinology, 4th Department of Pediatrics, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GreeceUnit of Pediatric Endocrinology, 4th Department of Pediatrics, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GreeceUnit of Pediatric Endocrinology, 4th Department of Pediatrics, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GreeceUnit of Pediatric Endocrinology, 4th Department of Pediatrics, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GreeceUnit of Pediatric Endocrinology, 4th Department of Pediatrics, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GreeceUnit of Pediatric Endocrinology, 4th Department of Pediatrics, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GreeceUnit of Pediatric Endocrinology, 4th Department of Pediatrics, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GreeceUnit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GreeceUnit of Pediatric Endocrinology, 4th Department of Pediatrics, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GreeceAndrogen Insensitivity Syndrome (AIS) and its heterogeneous phenotypes comprise the pieces of a challenging clinical problem. The lack of standardized guidelines results in controversies regarding the proper diagnostic and therapeutic approach, including the time and type of intervention. Due to its variable phenotype, AIS is not diagnosed at the proper age that would allow optimal psychological and medical support to the patient. Therapeutic approaches are not established, mainly due to the rarity of the disease. In addition, various social and ethical consequences may emerge. The aim of this double case report is to outline the difficulties that may rise during diagnostic, therapeutic, and psychological approach of AIS, especially concerning the handling of the relatives’ reaction.http://dx.doi.org/10.1155/2017/8313162
spellingShingle Filippa Pritsini
Georgios A. Kanakis
Ioannis Kyrgios
Eleni P. Kotanidou
Eleni Litou
Konstantina Mouzaki
Aggeliki Kleisarchaki
Dimitrios G. Goulis
Assimina Galli-Tsinopoulou
Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
Case Reports in Endocrinology
title Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title_full Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title_fullStr Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title_full_unstemmed Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title_short Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title_sort psychological aspects of androgen insensitivity syndrome two cases illustrating therapeutical challenges
url http://dx.doi.org/10.1155/2017/8313162
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