Enhancing the effects of nusinersen with cybernic treatment using Hybrid Assistive Limb (HAL) in spinal muscular atrophy: a real-world case series and exploratory cohort analysis

Enhancing the effects of nusinersen with cybernic treatment using Hybrid Assistive Limb (HAL) in spinal muscular atrophy: a real-world case series and exploratory cohort analysis

Abstract Background Nusinersen therapy for spinal muscular atrophy (SMA) provides significant functional improvement when initiated pre-symptomatically or early in life. However, challenges remain in diverse populations with longer disease duration. In Japan, innovative cybernic therapy with the Hyb...

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Bibliographic Details
Main Authors: Takashi Nakajima, Toshio Saito, Akihiro Hashiguchi, Taiki Nakabayashi, Kazuki Kodera, Kota Utsumi, Takeshi Kanayama, Haruka Urabe, Satoru Kinoshita
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Combined therapy
Cybernics
HAL
Hybrid assistive limb
Neurorehabilitation
Nusinersen
Online Access:https://doi.org/10.1186/s13023-025-03681-9
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https://doi.org/10.1186/s13023-025-03681-9

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