Collagen pre-strain discontinuity at the bone-Cartilage interface.
The bone-cartilage unit (BCU) is a universal feature in diarthrodial joints, which is mechanically-graded and subjected to shear and compressive strains. Changes in the BCU have been linked to osteoarthritis (OA) progression. Here we report existence of a physiological internal strain gradient (pre-...
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| Main Authors: | Waqas Badar, Husna Ali, Olivia N Brooker, Elis Newham, Tim Snow, Nicholas J Terrill, Gianluca Tozzi, Peter Fratzl, Martin M Knight, Himadri S Gupta |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0273832&type=printable |
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