Catalytic Enantioselective Synthesis of Axially Chiral Diaryl Ethers Via Asymmetric Povarov Reaction Enabled Desymmetrization
Abstract Axially chiral diaryl ethers represent a distinct class of atropisomers, characterized by a unique dual C─O axes system, which have been found in a variety of natural products, pharmaceuticals, and ligands. However, the catalytic enantioselective synthesis of these atropoisomers poses signi...
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| Main Authors: | Zidan Ye, Wansen Xie, Wei Liu, Changyu Zhou, Xiaoyu Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-09-01
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| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202403125 |
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