A Case Report of Coexistence of EGFR and ROS-1 Gene Mutations 
in Non-small Cell Lung Cancer

Lung cancer represents one of the most prevalent malignant tumors globally, and its treatment has entered the era of targeted therapy. The epidermal growth factor receptor (EGFR) mutation is a common type of genetic mutation in non-small cell lung cancer (NSCLC), while c-ros oncogene 1 receptor tyro...

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Bibliographic Details
Main Authors: Juan ZHAO, Jiaofeng YU, Ye FU, Yan ZHAO, Mingli ZHAO
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2025-06-01
Series:Chinese Journal of Lung Cancer
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Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2025.102.26
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Summary:Lung cancer represents one of the most prevalent malignant tumors globally, and its treatment has entered the era of targeted therapy. The epidermal growth factor receptor (EGFR) mutation is a common type of genetic mutation in non-small cell lung cancer (NSCLC), while c-ros oncogene 1 receptor tyrosine kinase (ROS-1) fusion mutation is a rare mutation site. Currently, there are few case reports on the coexistence of EGFR and ROS-1 gene mutations. This study reports a case of NSCLC with coexisting EGFR and ROS-1 gene mutations, aiming to provide relevant treatment strategies for clinical practice.
ISSN:1009-3419
1999-6187