Long-term outcome of bicuspid aortic valve repair using figure-of-8 hitch-up stitchesCentral MessagePerspective

Objective: To maximize successful repair of bicuspid aortic valves by adding figure-of-8 hitch-up stitches at commissures. Methods: From 2000 to 2022, bicuspid aortic valve repair was performed on 1112 patients at Cleveland Clinic, with 367 patients receiving figure-of-8 hitch-up stitches along with...

Full description

Saved in:
Bibliographic Details
Main Authors: Fei Xiang, MD, Lin Chen, BA, Raphaelle Chemtob, MD, Eric E. Roselli, MD, Shinya Unai, MD, Patrick Vargo, MD, Marijan Koprivanac, MD, A. Marc Gillinov, MD, Eugene H. Blackstone, MD, Jeevanantham Rajeswaran, PhD, Austin Firth, MS, Milind Y. Desai, MD, MBA, Brian Griffin, MD, Vidyasagar Kalahasti, MD, Lars G. Svensson, MD, PhD
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:JTCVS Techniques
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666250724000397
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849765406124802048
author Fei Xiang, MD
Lin Chen, BA
Raphaelle Chemtob, MD
Eric E. Roselli, MD
Shinya Unai, MD
Patrick Vargo, MD
Marijan Koprivanac, MD
A. Marc Gillinov, MD
Eugene H. Blackstone, MD
Jeevanantham Rajeswaran, PhD
Austin Firth, MS
Milind Y. Desai, MD, MBA
Brian Griffin, MD
Vidyasagar Kalahasti, MD
Lars G. Svensson, MD, PhD
author_facet Fei Xiang, MD
Lin Chen, BA
Raphaelle Chemtob, MD
Eric E. Roselli, MD
Shinya Unai, MD
Patrick Vargo, MD
Marijan Koprivanac, MD
A. Marc Gillinov, MD
Eugene H. Blackstone, MD
Jeevanantham Rajeswaran, PhD
Austin Firth, MS
Milind Y. Desai, MD, MBA
Brian Griffin, MD
Vidyasagar Kalahasti, MD
Lars G. Svensson, MD, PhD
author_sort Fei Xiang, MD
collection DOAJ
description Objective: To maximize successful repair of bicuspid aortic valves by adding figure-of-8 hitch-up stitches at commissures. Methods: From 2000 to 2022, bicuspid aortic valve repair was performed on 1112 patients at Cleveland Clinic, with 367 patients receiving figure-of-8 hitch-up stitches along with classical techniques, including Cabrol suture, cusp plication, raphe resection, and valve-sparing root replacement. Operative outcomes, repair durability, and survival were assessed in the figure-of-8 hitch-up stitches cohort, and outcomes were compared among 195 balancing-score-matched patient pairs who underwent bicuspid aortic valve repair with and without figure-of-8 hitch-up stitches. Results: Patients who underwent bicuspid aortic valve repair with figure-of-8 stitches had an operative mortality of 0.3% (1 of 367) and in-hospital reoperation for aortic valve dysfunction of 1.1% (4 of 367). At 10 years, prevalence of severe aortic regurgitation was 8.6%, mean gradient 24 mm Hg, freedom from aortic valve reoperation 75%, and survival 98%. In matched cohorts, operative mortality was similar (0.51% vs 0%; P > .9) as were morbidities, including in-hospital reoperation due to aortic valve dysfunction (1.0% vs 1.5%; P > .9). Comparable long-term outcomes were observed at 10 years (prevalence of severe aortic regurgitation of 8.7% vs 5.0% [P = .11], mean gradient 18 vs 17 mm Hg [P = .40]; freedom from aortic valve reoperation 80% vs 81% [P = .73]; and survival 99.5% vs 94.6% [P = .18]). Conclusions: Figure-of-8 hitch-up stitch is a safe bicuspid aortic valve repair technique. It increases the likelihood of a successful repair without increasing risk of cusp tear and achieves satisfactory long-term survival and durability when added to classical repair techniques.
format Article
id doaj-art-5739e653696b4a2e9eb2c4769408dd97
institution DOAJ
issn 2666-2507
language English
publishDate 2024-04-01
publisher Elsevier
record_format Article
series JTCVS Techniques
spelling doaj-art-5739e653696b4a2e9eb2c4769408dd972025-08-20T03:04:53ZengElsevierJTCVS Techniques2666-25072024-04-0124274010.1016/j.xjtc.2024.01.012Long-term outcome of bicuspid aortic valve repair using figure-of-8 hitch-up stitchesCentral MessagePerspectiveFei Xiang, MD0Lin Chen, BA1Raphaelle Chemtob, MD2Eric E. Roselli, MD3Shinya Unai, MD4Patrick Vargo, MD5Marijan Koprivanac, MD6A. Marc Gillinov, MD7Eugene H. Blackstone, MD8Jeevanantham Rajeswaran, PhD9Austin Firth, MS10Milind Y. Desai, MD, MBA11Brian Griffin, MD12Vidyasagar Kalahasti, MD13Lars G. Svensson, MD, PhD14Department of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, Ohio; Department of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing, ChinaDepartment of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, Ohio; Department of Quantitative Health Sciences, Lerner Research institute, Cleveland Clinic, Cleveland, OhioDepartment of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, Ohio; Department of Quantitative Health Sciences, Lerner Research institute, Cleveland Clinic, Cleveland, Ohio; Department of Cardiovascular Medicine, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Quantitative Health Sciences, Lerner Research institute, Cleveland Clinic, Cleveland, OhioDepartment of Cardiovascular Medicine, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Cardiovascular Medicine, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Cardiovascular Medicine, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OhioDepartment of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, Ohio; Address for reprints: Lars G. Svensson, MD, PhD, Department of Thoracic and Cardiovascular Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic, 9500 Euclid Ave, Desk J1-227, Cleveland, OH 44195.Objective: To maximize successful repair of bicuspid aortic valves by adding figure-of-8 hitch-up stitches at commissures. Methods: From 2000 to 2022, bicuspid aortic valve repair was performed on 1112 patients at Cleveland Clinic, with 367 patients receiving figure-of-8 hitch-up stitches along with classical techniques, including Cabrol suture, cusp plication, raphe resection, and valve-sparing root replacement. Operative outcomes, repair durability, and survival were assessed in the figure-of-8 hitch-up stitches cohort, and outcomes were compared among 195 balancing-score-matched patient pairs who underwent bicuspid aortic valve repair with and without figure-of-8 hitch-up stitches. Results: Patients who underwent bicuspid aortic valve repair with figure-of-8 stitches had an operative mortality of 0.3% (1 of 367) and in-hospital reoperation for aortic valve dysfunction of 1.1% (4 of 367). At 10 years, prevalence of severe aortic regurgitation was 8.6%, mean gradient 24 mm Hg, freedom from aortic valve reoperation 75%, and survival 98%. In matched cohorts, operative mortality was similar (0.51% vs 0%; P > .9) as were morbidities, including in-hospital reoperation due to aortic valve dysfunction (1.0% vs 1.5%; P > .9). Comparable long-term outcomes were observed at 10 years (prevalence of severe aortic regurgitation of 8.7% vs 5.0% [P = .11], mean gradient 18 vs 17 mm Hg [P = .40]; freedom from aortic valve reoperation 80% vs 81% [P = .73]; and survival 99.5% vs 94.6% [P = .18]). Conclusions: Figure-of-8 hitch-up stitch is a safe bicuspid aortic valve repair technique. It increases the likelihood of a successful repair without increasing risk of cusp tear and achieves satisfactory long-term survival and durability when added to classical repair techniques.http://www.sciencedirect.com/science/article/pii/S2666250724000397balancing scorereoperationsurvivalvalve-sparing root replacement
spellingShingle Fei Xiang, MD
Lin Chen, BA
Raphaelle Chemtob, MD
Eric E. Roselli, MD
Shinya Unai, MD
Patrick Vargo, MD
Marijan Koprivanac, MD
A. Marc Gillinov, MD
Eugene H. Blackstone, MD
Jeevanantham Rajeswaran, PhD
Austin Firth, MS
Milind Y. Desai, MD, MBA
Brian Griffin, MD
Vidyasagar Kalahasti, MD
Lars G. Svensson, MD, PhD
Long-term outcome of bicuspid aortic valve repair using figure-of-8 hitch-up stitchesCentral MessagePerspective
JTCVS Techniques
balancing score
reoperation
survival
valve-sparing root replacement
title Long-term outcome of bicuspid aortic valve repair using figure-of-8 hitch-up stitchesCentral MessagePerspective
title_full Long-term outcome of bicuspid aortic valve repair using figure-of-8 hitch-up stitchesCentral MessagePerspective
title_fullStr Long-term outcome of bicuspid aortic valve repair using figure-of-8 hitch-up stitchesCentral MessagePerspective
title_full_unstemmed Long-term outcome of bicuspid aortic valve repair using figure-of-8 hitch-up stitchesCentral MessagePerspective
title_short Long-term outcome of bicuspid aortic valve repair using figure-of-8 hitch-up stitchesCentral MessagePerspective
title_sort long term outcome of bicuspid aortic valve repair using figure of 8 hitch up stitchescentral messageperspective
topic balancing score
reoperation
survival
valve-sparing root replacement
url http://www.sciencedirect.com/science/article/pii/S2666250724000397
work_keys_str_mv AT feixiangmd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT linchenba longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT raphaellechemtobmd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT ericerosellimd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT shinyaunaimd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT patrickvargomd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT marijankoprivanacmd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT amarcgillinovmd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT eugenehblackstonemd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT jeevananthamrajeswaranphd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT austinfirthms longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT milindydesaimdmba longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT briangriffinmd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT vidyasagarkalahastimd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective
AT larsgsvenssonmdphd longtermoutcomeofbicuspidaorticvalverepairusingfigureof8hitchupstitchescentralmessageperspective