Modulation Effect of Peroxisome Proliferator-Activated Receptor Agonists on Lipid Droplet Proteins in Liver

Modulation Effect of Peroxisome Proliferator-Activated Receptor Agonists on Lipid Droplet Proteins in Liver

Peroxisome proliferator-activated receptor (PPAR) agonists are used for treating hyperglycemia and type 2 diabetes. However, the mechanism of action of these agonists is still under investigation. The lipid droplet-associated proteins FSP27/CIDEC and LSDP5, regulated directly by PPARγ and PPARα, are...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yun-Xia Zhu, Ming-Liang Zhang, Yuan Zhong, Chen Wang, Wei-Ping Jia
Format:	Article
Language:	English
Published:	Wiley 2016-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2016/8315454
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Pex3 promotes formation of peroxisome-peroxisome and peroxisome-lipid droplet contact sites
by: Lucía Amado, et al.
Published: (2025-07-01)

Acetoacetate Ameliorates Hepatic Fibrosis by Targeting Peroxisome Proliferator-Activated Receptor Gamma to Restore Lipid Droplets in Activated Hepatic Stellate Cells
by: Ya Zhou, et al.
Published: (2025-02-01)

Suppression of Rat Oral Carcinogenesis by Agonists of Peroxisome Proliferator Activated Receptor γ.
by: David L McCormick, et al.
Published: (2015-01-01)

Peroxisome Proliferators-Activated Receptor (PPAR) Modulators and Metabolic Disorders
by: Min-Chul Cho, et al.
Published: (2008-01-01)

Chondrosarcoma and Peroxisome Proliferator-Activated Receptor
by: K. Hashizume, et al.
Published: (2008-01-01)

Peroxisome Proliferator-Activated Receptors Associated with Nonalcoholic Fatty Liver Disease
by: Nan Wang, et al.
Published: (2017-01-01)

Pemafibrate modulates peroxisome proliferator-activated receptor alpha and prevents alcohol-associated liver disease in rats
by: Takashi Saito, et al.
Published: (2025-04-01)

Peroxisome Proliferator-Activated Receptor -β/δ, -γ Agonists and Resveratrol Modulate Hypoxia Induced Changes in Nuclear Receptor Activators of Muscle Oxidative Metabolism
by: Timothy R. H. Regnault, et al.
Published: (2010-01-01)

Regulation of Peroxisome Proliferator-Activated Receptors by E6-Associated Protein
by: Lakshmi Gopinathan, et al.
Published: (2008-01-01)

Involvement of the Retinoid X Receptor Ligand in the Anti-Inflammatory Effect Induced by Peroxisome Proliferator-Activated Receptor 𝜸 Agonist In Vivo
by: Atsuki Yamamoto, et al.
Published: (2011-01-01)

Cellular and Biophysical Pipeline for the Screening of Peroxisome Proliferator-Activated Receptor Beta/Delta Agonists: Avoiding False Positives
by: Natália Bernardi Videira, et al.
Published: (2018-01-01)

Peroxisome Proliferator-Activated Receptors and Shock State
by: Emanuela Esposito, et al.
Published: (2006-01-01)

Interactions between Human Liver Fatty Acid Binding Protein and Peroxisome Proliferator Activated Receptor Selective Drugs
by: Tony Velkov
Published: (2013-01-01)

Peroxisome Proliferator-Activated Receptor Modulation during Metabolic Diseases and Cancers: Master and Minions
by: Salvatore Giovanni Vitale, et al.
Published: (2016-01-01)

Peroxisome Proliferator-Activated Receptors and Progression of Colorectal Cancer
by: Dingzhi Wang, et al.
Published: (2008-01-01)

Peroxisome Proliferator-Activated Receptors in HBV-Related Infection
by: Laurent Dubuquoy, et al.
Published: (2009-01-01)

Peroxisome Proliferator-Activated Receptors in HCV-Related Infection
by: Sébastien Dharancy, et al.
Published: (2009-01-01)

Protective Effects of Peroxisome Proliferator-Activated Receptor-α Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes
by: Ke Chen, et al.
Published: (2012-01-01)

Neuroprotective Potential of Peroxisome Proliferator Activated Receptor-α Agonist in Cognitive Impairment in Parkinson’s Disease: Behavioral, Biochemical, and PBPK Profile
by: Dedeepya Uppalapati, et al.
Published: (2014-01-01)

Peroxisome Proliferator-Activated Receptor-γ Is Critical to Cardiac Fibrosis
by: Huang-Jun Liu, et al.
Published: (2016-01-01)

Peroxisome Proliferator-Activated Receptors as a Therapeutic Target in Asthma
by: Oxana Yu. Kytikova, et al.
Published: (2020-01-01)

Role of Peroxisome Proliferator-Activated Receptor γ in Ocular Diseases
by: Su Zhang, et al.
Published: (2015-01-01)

Role of Peroxisome Proliferator-Activated Receptor-γ in Vascular Inflammation
by: Kousei Ohshima, et al.
Published: (2012-01-01)

Effect of Pemafibrate, a Selective Peroxisome Proliferator-activated Receptor ? Modulator (SPPARM?), on the Lipid Profile, Liver Function, and Liver Fibrosis among Patients with Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
by: Mona Hassan, et al.
Published: (2025-06-01)

Peroxisome Proliferator-Activated Receptor Delta: A Conserved Director of Lipid Homeostasis through Regulation of the Oxidative Capacity of Muscle
by: Maria Moreno, et al.
Published: (2008-01-01)

The Role of Peroxisome Proliferator-Activated Receptors in the Esophageal, Gastric, and Colorectal Cancer
by: Alessandra Fucci, et al.
Published: (2012-01-01)

Nuclear Control of the Inflammatory Response in Mammals by Peroxisome Proliferator-Activated Receptors
by: Stéphane Mandard, et al.
Published: (2013-01-01)

Peroxisome Proliferator-Activated Receptor Genetic Polymorphisms and Nonalcoholic Fatty Liver Disease: Any Role in Disease Susceptibility?
by: Paola Dongiovanni, et al.
Published: (2013-01-01)

Exploring the Role of Peroxisome Proliferator-Activated Receptors and Endothelial Dysfunction in Metabolic Dysfunction-Associated Steatotic Liver Disease
by: Ana Paula Madariaga Traconis, et al.
Published: (2024-12-01)

Potential involvement of peroxisome proliferator-activated receptors in the inhibition of mammary lipid synthesis during diet-induced milk fat depression
by: A. Haile, et al.
Published: (2025-02-01)

Oleic acid promotes lipid accumulation in bovine adipocytes: the role of peroxisome proliferator-activated receptor alpha (PPARα) signaling
by: U. Abou-Rjeileh, et al.
Published: (2025-05-01)

Peroxisome Proliferator-Activated Receptors Alpha, Beta, and Gamma mRNA and Protein Expression in Human Fetal Tissues
by: Barbara D. Abbott, et al.
Published: (2010-01-01)

Induction of Metastatic Gastric Cancer by Peroxisome Proliferator-Activated Receptorδ Activation
by: Claire B. Pollock, et al.
Published: (2010-01-01)

The Role of Peroxisome Proliferator-Activated Receptors in the Development and Physiology of Gametes and Preimplantation Embryos
by: Jaou-Chen Huang
Published: (2008-01-01)

The Versatile Role of Peroxisome Proliferator-Activated Receptors in Immune-Mediated Intestinal Diseases
by: Edit Posta, et al.
Published: (2024-10-01)

Peptide Helix-Y12 as Potential Effector for Peroxisome Proliferator-Activated Receptors
by: Mauricio Carrillo-Tripp, et al.
Published: (2023-01-01)

Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors
by: Tengis S. Pavlov, et al.
Published: (2010-01-01)

Activating Effect of Benzbromarone, a Uricosuric Drug, on Peroxisome Proliferator-Activated Receptors
by: Chiyoko Kunishima, et al.
Published: (2007-01-01)

The Association of Peroxisome Proliferator-Activated Receptor δ and Additional Gene-Gene Interaction with C-Reactive Protein in Chinese Population
by: Xiao-Ying Ding, et al.
Published: (2016-01-01)

Erratum to “Peroxisome Proliferator-Activated Receptors Alpha, Beta, and Gamma mRNA and Protein Expression in Human Fetal Tissues”
by: Barbara D. Abbott, et al.
Published: (2010-01-01)