Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg Patient
Limited available data for dosing in obesity of the medicines used in this case are discussed, with the emphasis on ertapenem. The case illustrates the difficulties in dosing medicines to morbidly overweight patients. The number of such patients is increasing but data on adequate doses of medicines...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2017/5310768 |
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| _version_ | 1832560440166580224 |
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| author | Jana Lass Kadri Tamme Karin Kipper Joel Starkopf |
| author_facet | Jana Lass Kadri Tamme Karin Kipper Joel Starkopf |
| author_sort | Jana Lass |
| collection | DOAJ |
| description | Limited available data for dosing in obesity of the medicines used in this case are discussed, with the emphasis on ertapenem. The case illustrates the difficulties in dosing medicines to morbidly overweight patients. The number of such patients is increasing but data on adequate doses of medicines are scarce. We demonstrate that ertapenem 1,5 g i.v. once daily provided adequate drug exposure for susceptible bacteria in a 250 kg patient with normal renal function. The case suggests the usefulness of therapeutic drug monitoring of antibiotics, especially in critically ill patients. |
| format | Article |
| id | doaj-art-57387d3268404fc7aa68086bb54478cb |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-57387d3268404fc7aa68086bb54478cb2025-02-03T01:27:34ZengWileyCase Reports in Critical Care2090-64202090-64392017-01-01201710.1155/2017/53107685310768Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg PatientJana Lass0Kadri Tamme1Karin Kipper2Joel Starkopf3Tartu University Hospital Pharmacy, Tartu, EstoniaClinic of Anaesthesiology and Intensive Care, Tartu University Hospital, Tartu, EstoniaInstitute of Chemistry, University of Tartu, Tartu, EstoniaClinic of Anaesthesiology and Intensive Care, Tartu University Hospital, Tartu, EstoniaLimited available data for dosing in obesity of the medicines used in this case are discussed, with the emphasis on ertapenem. The case illustrates the difficulties in dosing medicines to morbidly overweight patients. The number of such patients is increasing but data on adequate doses of medicines are scarce. We demonstrate that ertapenem 1,5 g i.v. once daily provided adequate drug exposure for susceptible bacteria in a 250 kg patient with normal renal function. The case suggests the usefulness of therapeutic drug monitoring of antibiotics, especially in critically ill patients.http://dx.doi.org/10.1155/2017/5310768 |
| spellingShingle | Jana Lass Kadri Tamme Karin Kipper Joel Starkopf Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg Patient Case Reports in Critical Care |
| title | Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg Patient |
| title_full | Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg Patient |
| title_fullStr | Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg Patient |
| title_full_unstemmed | Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg Patient |
| title_short | Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg Patient |
| title_sort | dosing of ertapenem in an extreme obesity a case report of 250 kg patient |
| url | http://dx.doi.org/10.1155/2017/5310768 |
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