Synthesis, Microstructure, Optical Properties, and Sensitive Amoxicillin Detection of Carbon Dots
The detection of amoxicillin has been successfully carried out using C-dot fluorescence probes made from d-glucose and urea. The fluorescence probe has an intense bright blue emission under UV light at 395 nm and and depends on the excitation and depends on the excitation. Raman studies successful...
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Department of Chemistry, Pattimura University
2025-05-01
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| Series: | Indonesian Journal of Chemical Research |
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| Online Access: | https://ojs3.unpatti.ac.id/index.php/ijcr/article/view/18151 |
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| author | Yuni Aldriani Lubis Saharman Gea Muhammad Frassetia Lubis Woei Wu Larry Pai Marpongahtun Marpongahtun |
| author_facet | Yuni Aldriani Lubis Saharman Gea Muhammad Frassetia Lubis Woei Wu Larry Pai Marpongahtun Marpongahtun |
| author_sort | Yuni Aldriani Lubis |
| collection | DOAJ |
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The detection of amoxicillin has been successfully carried out using C-dot fluorescence probes made from d-glucose and urea. The fluorescence probe has an intense bright blue emission under UV light at 395 nm and and depends on the excitation and depends on the excitation. Raman studies successfully showed a D peak at 1381 cm-1 and a G peak at 1586 cm-1 associated with graphitic and amorphous structures. The absorption peaks in UV-vis spectroscopy confirm transitions at 275 nm (π → π*) and 322 nm (n → π*) with the presence of conjugated C=C and carbonyl (C=O) functional groups. The results of the fluorescence test show a bright blue color, with its intensity measured at an excitation of 365 nm. This can be attributed to nitrogen incorporation on the surface of the C-dots derived from urea, resulting in a quantum yield of 54%. This fluorescence probe is highly sensitive in detecting amoxicillin, as evidenced by the successful detection of AMX at concentrations of 10–30 μM and a resulting LOD of 5.75443×10−7 nM. The microstructure shows a uniform size of C-dot nanoparticles, and C-dot modeling was created. C-dot probes have an LOD of 5.75443×10−7 nM, indicating high sensitivity in detecting AMX.
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| format | Article |
| id | doaj-art-573153ed0d52482183b99bd81c41ba2a |
| institution | OA Journals |
| issn | 2338-5359 2614-2627 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Department of Chemistry, Pattimura University |
| record_format | Article |
| series | Indonesian Journal of Chemical Research |
| spelling | doaj-art-573153ed0d52482183b99bd81c41ba2a2025-08-20T02:22:34ZengDepartment of Chemistry, Pattimura UniversityIndonesian Journal of Chemical Research2338-53592614-26272025-05-0113110.30598/ijcr.2025.13-yunSynthesis, Microstructure, Optical Properties, and Sensitive Amoxicillin Detection of Carbon DotsYuni Aldriani Lubis0Saharman Gea1Muhammad Frassetia Lubis2Woei Wu Larry Pai3Marpongahtun Marpongahtun4Postgraduate School, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Jl. Bioteknologi No.1, Medan, 20155, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Jl. Bioteknologi No. 1 Medan, 20155, IndonesiaCenter for Condensed Matter Sciences, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 10617, TaiwanCenter for Condensed Matter Sciences, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 10617, TaiwanDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Jl. Bioteknologi No. 1 Medan, 20155, Indonesia The detection of amoxicillin has been successfully carried out using C-dot fluorescence probes made from d-glucose and urea. The fluorescence probe has an intense bright blue emission under UV light at 395 nm and and depends on the excitation and depends on the excitation. Raman studies successfully showed a D peak at 1381 cm-1 and a G peak at 1586 cm-1 associated with graphitic and amorphous structures. The absorption peaks in UV-vis spectroscopy confirm transitions at 275 nm (π → π*) and 322 nm (n → π*) with the presence of conjugated C=C and carbonyl (C=O) functional groups. The results of the fluorescence test show a bright blue color, with its intensity measured at an excitation of 365 nm. This can be attributed to nitrogen incorporation on the surface of the C-dots derived from urea, resulting in a quantum yield of 54%. This fluorescence probe is highly sensitive in detecting amoxicillin, as evidenced by the successful detection of AMX at concentrations of 10–30 μM and a resulting LOD of 5.75443×10−7 nM. The microstructure shows a uniform size of C-dot nanoparticles, and C-dot modeling was created. C-dot probes have an LOD of 5.75443×10−7 nM, indicating high sensitivity in detecting AMX. https://ojs3.unpatti.ac.id/index.php/ijcr/article/view/18151C-dotsmicrostructurehydrothermalraman spectroscopyAMXoptical properies |
| spellingShingle | Yuni Aldriani Lubis Saharman Gea Muhammad Frassetia Lubis Woei Wu Larry Pai Marpongahtun Marpongahtun Synthesis, Microstructure, Optical Properties, and Sensitive Amoxicillin Detection of Carbon Dots Indonesian Journal of Chemical Research C-dots microstructure hydrothermal raman spectroscopy AMX optical properies |
| title | Synthesis, Microstructure, Optical Properties, and Sensitive Amoxicillin Detection of Carbon Dots |
| title_full | Synthesis, Microstructure, Optical Properties, and Sensitive Amoxicillin Detection of Carbon Dots |
| title_fullStr | Synthesis, Microstructure, Optical Properties, and Sensitive Amoxicillin Detection of Carbon Dots |
| title_full_unstemmed | Synthesis, Microstructure, Optical Properties, and Sensitive Amoxicillin Detection of Carbon Dots |
| title_short | Synthesis, Microstructure, Optical Properties, and Sensitive Amoxicillin Detection of Carbon Dots |
| title_sort | synthesis microstructure optical properties and sensitive amoxicillin detection of carbon dots |
| topic | C-dots microstructure hydrothermal raman spectroscopy AMX optical properies |
| url | https://ojs3.unpatti.ac.id/index.php/ijcr/article/view/18151 |
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