Fluctuating or progressive hearing loss in the middle-to-high frequencies may suggest the neurotologic endotype of perilymphatic fistula without antecedent traumatic events

BackgroundIdiopathic sudden sensorineural hearing loss (ISSNHL) is a common clinical condition. Recent studies indicate that approximately 20% of ISSNHL cases may involve perilymphatic fistula (PLF). The detection of Cochlin-tomoprotein (CTP) in middle-ear lavage samples confirms the diagnosis of PL...

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Bibliographic Details
Main Authors:	Han Matsuda, Yukihide Maeda, Tomoyasu Kitahara, Masafumi Sawada, Hiroe Kudo, Kei Sakamoto, Atsuya Takayama, Tetsuo Ikezono
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Series:	Frontiers in Neurology
Subjects:	Perilymphatic fistula antecedent traumatic events idiopathic sudden sensorineural hearing loss Cochlin-tomoprotein fluctuating hearing loss progressive hearing loss
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2025.1571379/full
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Fluctuating or progressive hearing loss in the middle-to-high frequencies may suggest the neurotologic endotype of perilymphatic fistula without antecedent traumatic events

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