Mechanistic insights into the role of RNA demethylase ALKBH5 in malignant tumor therapy

Abstract m6A RNA methylation represents the most prevalent epitranscriptomic modification and modulates diverse dimensions of RNA metabolism. As a dynamic and reversible post-transcriptional mark, m6A is broadly distributed across multiple RNA types, including mRNA, ribosomal RNA (rRNA), microRNA (m...

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Bibliographic Details
Main Authors: Ruijie An, Yingjie Shao, Wendong Gu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Translational Medicine
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Online Access:https://doi.org/10.1186/s12967-025-06938-w
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