A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten

Gluten, known as the major allergen in wheat, has gained increasing concerns in industrialized countries, resulting in an urgent need for accurate, high-sensitive, and on-site detection of wheat gluten in complex food systems. Herein, we proposed a silver nanoparticles (AgNPs)/metal-organic framewor...

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Main Authors: Linglin Fu, Yanzhuo Du, Jinru Zhou, Huan Li, Minzi Wang, Yanbo Wang
Format: Article
Language:English
Published: Tsinghua University Press 2024-03-01
Series:Food Science and Human Wellness
Subjects:
Online Access:https://www.sciopen.com/article/10.26599/FSHW.2022.9250057
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author Linglin Fu
Yanzhuo Du
Jinru Zhou
Huan Li
Minzi Wang
Yanbo Wang
author_facet Linglin Fu
Yanzhuo Du
Jinru Zhou
Huan Li
Minzi Wang
Yanbo Wang
author_sort Linglin Fu
collection DOAJ
description Gluten, known as the major allergen in wheat, has gained increasing concerns in industrialized countries, resulting in an urgent need for accurate, high-sensitive, and on-site detection of wheat gluten in complex food systems. Herein, we proposed a silver nanoparticles (AgNPs)/metal-organic framework (MOF) substrate-based surface-enhanced Raman scattering (SERS) sensor for the high-sensitive on-site detection of wheat gluten. The detection occurred on the newly in-situ synthesized AgNPs/MOF-modified SERS substrate, providing an enhancement factor (EF) of 1.89 × 105. Benefitting from the signal amplification function of AgNPs/MOF and the superiority of SERS, this sensor represented high sensitivity performance and a wide detection range from 1 × 10-15 mol/L to 2 × 10-6 mol/L with a detection limit of 1.16 × 10-16 mol/L, which allowed monitoring the trace of wheat gluten in complex food system without matrix interference. This reliable sandwich SERS sensor may provide a promising platform for high-sensitive, accurate, and on-site detection of allergens in the field of food safety.
format Article
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institution Kabale University
issn 2213-4530
language English
publishDate 2024-03-01
publisher Tsinghua University Press
record_format Article
series Food Science and Human Wellness
spelling doaj-art-56f817d1a3304e0596d6c2f68e33fda42025-08-20T03:26:25ZengTsinghua University PressFood Science and Human Wellness2213-45302024-03-0113268168710.26599/FSHW.2022.9250057A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat glutenLinglin Fu0Yanzhuo Du1Jinru Zhou2Huan Li3Minzi Wang4Yanbo Wang5Food Safety Key Laboratory of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, ChinaFood Safety Key Laboratory of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, ChinaFood Safety Key Laboratory of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, ChinaFood Safety Key Laboratory of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, ChinaZhejiang Dien Biotech Co., Ltd., Hangzhou 310030, ChinaFood Safety Key Laboratory of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, ChinaGluten, known as the major allergen in wheat, has gained increasing concerns in industrialized countries, resulting in an urgent need for accurate, high-sensitive, and on-site detection of wheat gluten in complex food systems. Herein, we proposed a silver nanoparticles (AgNPs)/metal-organic framework (MOF) substrate-based surface-enhanced Raman scattering (SERS) sensor for the high-sensitive on-site detection of wheat gluten. The detection occurred on the newly in-situ synthesized AgNPs/MOF-modified SERS substrate, providing an enhancement factor (EF) of 1.89 × 105. Benefitting from the signal amplification function of AgNPs/MOF and the superiority of SERS, this sensor represented high sensitivity performance and a wide detection range from 1 × 10-15 mol/L to 2 × 10-6 mol/L with a detection limit of 1.16 × 10-16 mol/L, which allowed monitoring the trace of wheat gluten in complex food system without matrix interference. This reliable sandwich SERS sensor may provide a promising platform for high-sensitive, accurate, and on-site detection of allergens in the field of food safety.https://www.sciopen.com/article/10.26599/FSHW.2022.9250057wheat allergyglutensurface-enhanced raman scatteringmetal-organic frameworkdna recognition
spellingShingle Linglin Fu
Yanzhuo Du
Jinru Zhou
Huan Li
Minzi Wang
Yanbo Wang
A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten
Food Science and Human Wellness
wheat allergy
gluten
surface-enhanced raman scattering
metal-organic framework
dna recognition
title A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten
title_full A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten
title_fullStr A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten
title_full_unstemmed A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten
title_short A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten
title_sort novel agnps mof substrate based sers sensor for high sensitive on site detection of wheat gluten
topic wheat allergy
gluten
surface-enhanced raman scattering
metal-organic framework
dna recognition
url https://www.sciopen.com/article/10.26599/FSHW.2022.9250057
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