Nucleic acid therapeutics: Past, present, and future
Nucleic acid therapeutics have become increasingly recognized in recent years for their capability to target both coding and non-coding sequences. Several types of nucleic acid modalities, including siRNA, mRNA, aptamer, along with antisense oligo, have been approved by regulatory bodies for therape...
Saved in:
| Main Authors: | Sajid Naeem, Ju Zhang, Yang Zhang, Yu Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-03-01
|
| Series: | Molecular Therapy: Nucleic Acids |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253124003275 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Endosomal Escape and Nuclear Localization: Critical Barriers for Therapeutic Nucleic Acids
by: Randall Allen, et al.
Published: (2024-12-01) -
In vivo efficacy and safety of systemically administered serinol nucleic acid-modified antisense oligonucleotides in mouse kidney
by: Toshiki Tsuboi, et al.
Published: (2025-03-01) -
The RNA revolution in medicine: from gene regulation to clinical therapeutics
by: Jiwon Jeong, et al.
Published: (2025-12-01) -
Design and screening of novel endosomal escape compounds that enhance functional delivery of oligonucleotides in vitro
by: H. Yesid Estupiñán, et al.
Published: (2025-06-01) -
A dual fluorescence-based reporter assay for real-time determination of siRNA- and antisense oligonucleotide-mediated knockdown
by: Felix Heß, et al.
Published: (2025-09-01)