Prospective observational study to evaluate the feasibility of the mobile app for mild cognitive impairment detection and screening

IntroductionThe increasing prevalence of dementia in aging populations necessitates effective and accessible cognitive screening tools. This study aimed to evaluate the feasibility and reliability of a newly developed mobile app for detecting and screening mild cognitive impairment (MCI).MethodsThe...

Full description

Saved in:
Bibliographic Details
Main Authors: Reo Hamaguchi, Seiji Hongo, Naoto Doi, Hisamitsu Ide, Ryozo Saito, Junji Kishimoto, Nobuhiro Handa, Shigeo Horie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Digital Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fdgth.2025.1535900/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1825206151409565696
author Reo Hamaguchi
Seiji Hongo
Naoto Doi
Hisamitsu Ide
Ryozo Saito
Junji Kishimoto
Nobuhiro Handa
Shigeo Horie
author_facet Reo Hamaguchi
Seiji Hongo
Naoto Doi
Hisamitsu Ide
Ryozo Saito
Junji Kishimoto
Nobuhiro Handa
Shigeo Horie
author_sort Reo Hamaguchi
collection DOAJ
description IntroductionThe increasing prevalence of dementia in aging populations necessitates effective and accessible cognitive screening tools. This study aimed to evaluate the feasibility and reliability of a newly developed mobile app for detecting and screening mild cognitive impairment (MCI).MethodsThe mobile app, developed by LifeQuest Co., Ltd. (Minato-ku, Tokyo), is an original tool inspired by the Japanese version of the Montreal Cognitive Assessment (MoCA-J). A prospective observational study was conducted with 20 participants, including healthy individuals, MCI patients, and those with mild to moderate-severe dementia. Participants completed both the mobile app and the MoCA-J in a randomized order within a two-week period, with a minimum one-day interval between tests.Results and conclusionThe intraclass correlation coefficient (ICC) between the mobile app and the MoCA-J was 0.956 (95% CI: 0.89-0.983), demonstrating a very high level of correlation. All participants successfully completed the mobile app assessment, highlighting its feasibility across various cognitive levels. Although minor technical issues and usability challenges were identified, the results support the mobile app as a reliable and user-friendly alternative for cognitive screening. Further studies with larger sample sizes are necessary to validate these findings and refine the app for broader clinical use.
format Article
id doaj-art-56f35f8d67ec48df9c21edc1635eb4fe
institution Kabale University
issn 2673-253X
language English
publishDate 2025-02-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Digital Health
spelling doaj-art-56f35f8d67ec48df9c21edc1635eb4fe2025-02-07T13:32:23ZengFrontiers Media S.A.Frontiers in Digital Health2673-253X2025-02-01710.3389/fdgth.2025.15359001535900Prospective observational study to evaluate the feasibility of the mobile app for mild cognitive impairment detection and screeningReo Hamaguchi0Seiji Hongo1Naoto Doi2Hisamitsu Ide3Ryozo Saito4Junji Kishimoto5Nobuhiro Handa6Shigeo Horie7Department of Digital Therapeutics, Graduate School of Medicine, Juntendo University, Tokyo, JapanNanko Clinic of Psychiatry, Fukushima, JapanIchigaya Himorogi Clinic, Tokyo, JapanDepartment of Digital Therapeutics, Graduate School of Medicine, Juntendo University, Tokyo, JapanLife Quest Inc., Tokyo, JapanCenter for Clinical and Translational Research, Kyushu University Hospital, Fukuoka, JapanDepartment of Digital Therapeutics, Graduate School of Medicine, Juntendo University, Tokyo, JapanDepartment of Digital Therapeutics, Graduate School of Medicine, Juntendo University, Tokyo, JapanIntroductionThe increasing prevalence of dementia in aging populations necessitates effective and accessible cognitive screening tools. This study aimed to evaluate the feasibility and reliability of a newly developed mobile app for detecting and screening mild cognitive impairment (MCI).MethodsThe mobile app, developed by LifeQuest Co., Ltd. (Minato-ku, Tokyo), is an original tool inspired by the Japanese version of the Montreal Cognitive Assessment (MoCA-J). A prospective observational study was conducted with 20 participants, including healthy individuals, MCI patients, and those with mild to moderate-severe dementia. Participants completed both the mobile app and the MoCA-J in a randomized order within a two-week period, with a minimum one-day interval between tests.Results and conclusionThe intraclass correlation coefficient (ICC) between the mobile app and the MoCA-J was 0.956 (95% CI: 0.89-0.983), demonstrating a very high level of correlation. All participants successfully completed the mobile app assessment, highlighting its feasibility across various cognitive levels. Although minor technical issues and usability challenges were identified, the results support the mobile app as a reliable and user-friendly alternative for cognitive screening. Further studies with larger sample sizes are necessary to validate these findings and refine the app for broader clinical use.https://www.frontiersin.org/articles/10.3389/fdgth.2025.1535900/fullmobile appsmartphone appneuropsychological testscognitive disordersmild cognitive impairmentAlzheimer's disease
spellingShingle Reo Hamaguchi
Seiji Hongo
Naoto Doi
Hisamitsu Ide
Ryozo Saito
Junji Kishimoto
Nobuhiro Handa
Shigeo Horie
Prospective observational study to evaluate the feasibility of the mobile app for mild cognitive impairment detection and screening
Frontiers in Digital Health
mobile app
smartphone app
neuropsychological tests
cognitive disorders
mild cognitive impairment
Alzheimer's disease
title Prospective observational study to evaluate the feasibility of the mobile app for mild cognitive impairment detection and screening
title_full Prospective observational study to evaluate the feasibility of the mobile app for mild cognitive impairment detection and screening
title_fullStr Prospective observational study to evaluate the feasibility of the mobile app for mild cognitive impairment detection and screening
title_full_unstemmed Prospective observational study to evaluate the feasibility of the mobile app for mild cognitive impairment detection and screening
title_short Prospective observational study to evaluate the feasibility of the mobile app for mild cognitive impairment detection and screening
title_sort prospective observational study to evaluate the feasibility of the mobile app for mild cognitive impairment detection and screening
topic mobile app
smartphone app
neuropsychological tests
cognitive disorders
mild cognitive impairment
Alzheimer's disease
url https://www.frontiersin.org/articles/10.3389/fdgth.2025.1535900/full
work_keys_str_mv AT reohamaguchi prospectiveobservationalstudytoevaluatethefeasibilityofthemobileappformildcognitiveimpairmentdetectionandscreening
AT seijihongo prospectiveobservationalstudytoevaluatethefeasibilityofthemobileappformildcognitiveimpairmentdetectionandscreening
AT naotodoi prospectiveobservationalstudytoevaluatethefeasibilityofthemobileappformildcognitiveimpairmentdetectionandscreening
AT hisamitsuide prospectiveobservationalstudytoevaluatethefeasibilityofthemobileappformildcognitiveimpairmentdetectionandscreening
AT ryozosaito prospectiveobservationalstudytoevaluatethefeasibilityofthemobileappformildcognitiveimpairmentdetectionandscreening
AT junjikishimoto prospectiveobservationalstudytoevaluatethefeasibilityofthemobileappformildcognitiveimpairmentdetectionandscreening
AT nobuhirohanda prospectiveobservationalstudytoevaluatethefeasibilityofthemobileappformildcognitiveimpairmentdetectionandscreening
AT shigeohorie prospectiveobservationalstudytoevaluatethefeasibilityofthemobileappformildcognitiveimpairmentdetectionandscreening