Intracristal space proteome mapping using super-resolution proximity labeling with isotope-coded probes

Intracristal space proteome mapping using super-resolution proximity labeling with isotope-coded probes

Abstract Proximity labeling with engineered ascorbate peroxidase (APEX) has been widely used to identify proteomes within various membrane-enclosed subcellular organelles. However, constructing protein distribution maps between two non-partitioned proximal spaces remains challenging with the current...

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Main Authors: Myeong-Gyun Kang, Sanghee Shin, Dong-Gi Jang, Ohyeon Kwon, Song-Yi Lee, Pratyush Kumar Mishra, Minkyo Jung, Ji Young Mun, Jung-Min Kee, Jong-Seo Kim, Hyun-Woo Rhee
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62756-0
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