Transition Metal‐Free Direct Electrochemical Carboxylation of Organic Halides Using a Sacrificial Magnesium Anode: Straightforward Synthesis of Carboxylic Acids
Abstract The direct electrochemical carboxylation of aryl, benzyl and alkyl halides by CO2 is described using a magnesium anode and a nickel foam cathode in an undivided cell. The process employs a sacrificial anode and does not require the additional use of a transition metal catalyst or demanding...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2025-07-01
|
| Series: | ChemistryOpen |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/open.202400426 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Abstract The direct electrochemical carboxylation of aryl, benzyl and alkyl halides by CO2 is described using a magnesium anode and a nickel foam cathode in an undivided cell. The process employs a sacrificial anode and does not require the additional use of a transition metal catalyst or demanding conditions, as the reactions are carried out under galvanostatic mode, at −10 °C and with commercial DMF. Under these operationally simple conditions, an important range of carboxylic acids are affordable. Mechanistic investigation account for the in situ generation of a carbanionic species that is not a simple organomagnesium halide. |
|---|---|
| ISSN: | 2191-1363 |