Montbretia flowers as a source of bioactive crocins: Biotechnology tools and delivery systems

Montbretia flowers as a source of bioactive crocins: Biotechnology tools and delivery systems

Crocins are potent antioxidants with significant therapeutic potential, exhibiting anti-inflammatory, anticancer, and antidepressant properties. The ornamental plant Crocos-mia x crocosmiiflora is widely cultivated for its aromatic and vibrant flowers. In this study, we identified unique crocins as...

Full description

Saved in:

Bibliographic Details
Main Authors:	Lucía Morote, Cristian Martínez Martínez Fajardo, María Mondéjar López, Elena Moreno-Gimenez, Ángela Rubio-Moraga, Olivia Costantina Demurtas, Gianfranco Diretto, Enrique Niza, Verónica Aragonés, Alberto López Jiménez, José-Antonio Daròs, Oussama Ahrazem, Lourdes Gómez-Gómez
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Series:	Biotechnology Reports
Subjects:	CCD Crocin Crocosmia x crocosmiiflora Exosomes Inflammation Liposomes
Online Access:	http://www.sciencedirect.com/science/article/pii/S2215017X25000189
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Natural CCD2 Variants and RNA Interference for Boosting Crocin Biosynthesis in Tomato
by: Elena Moreno-Giménez, et al.
Published: (2025-07-01)

Metabolic engineering of crocins and picrocrocin apocarotenoids in potato group phureja
by: Lourdes Gómez‐Gómez, et al.
Published: (2024-12-01)

Impact of Crocin Supplementation on Serum level of Zinc, Coppe, and Magnesium levels in Individuals with Metabolic Syndrome
by: Maryam Saberi-Karimian, et al.
Published: (2025-06-01)

Effects of Crocin on Brain Neurotrophins, Cognition, Balance and Pain in Toxic-Induced Demyelination Model
by: Rouholah Fatemi, et al.
Published: (2024-04-01)

Evaluation of therapeutic effects of Crocin in patients with polycystic ovary syndrome: A randomized Double-Blind clinical trial
by: Fatemeh Saghafi, et al.
Published: (2025-08-01)

Investigation of The Effects of Intracerebroventricular Crocin Injection on Extinction and Reinstatement Periods Following Morphine Conditioning in Male Rats: A Behavioural, Biochemical, and Histological Study
by: Mahdiye Faraji, et al.
Published: (2025-08-01)

Molecular mechanisms involved in the anticancer activity of crocin and crocetin, two bioactive compounds found in saffron
by: Mohammad Mehdi Haghighat_Lari, et al.
Published: (2024-10-01)

Crocin promotes ferroptosis in gastric cancer via the Nrf2/GGTLC2 pathway
by: Nan Yan, et al.
Published: (2025-03-01)

The effect of aerobic exercise and crocin consumption on the gene expression of BDNF, TrkB, dopamine, and serotonin in the cerebral cortex of rats induced with methamphetamine
by: Soudabeh Nourolapour, et al.
Published: (2024-06-01)

Investigation and Evaluation of Dually Loaded Niosomes Containing Crocin and Omega-3 by Heating & Bubble Method
by: Parisa Mardani, et al.
Published: (2025-05-01)

Effects of Crocin, Azithromycin, and Their Co-administration on Sciatic Nerve Injury in Rats
by: Mohammad Ebrahim Abbaszadeh, et al.
Published: (2024-10-01)

Efficient purification of CrocinI from saffron stigmas using antisolvent precipitation to implications for food technology
by: Elmira Fotouhi, et al.
Published: (2025-08-01)

Crocin improves post-thaw quality, fertility-associated gene expression and fertilization potential of buffalo bull sperm
by: Amjad Riaz, et al.
Published: (2023-11-01)

Cardioprotective effect of crocin in patients with breast cancer receiving anthracycline-based chemotherapy: A randomized, double-blind, placebo-controlled study
by: Xinye Li, et al.
Published: (2025-03-01)

Comparative Effects of Crocin and Losartan on RAGE, TGF‐β, TNF‐α Gene Expression and Histopathological Changes of the Liver Tissue in Rats With Diabetes
by: Shahnaz Rajabi, et al.
Published: (2025-01-01)

Supplementing Freezing Medium with Crocin Exerts a Protective Effect on Bovine Spermatozoa Through the Modulation of a Heat Shock-Mediated Apoptotic Pathway
by: Vasiliki Sapanidou, et al.
Published: (2025-03-01)

Crocin nano-chitosan-coated compound mitigates hippocampal blood-brain barrier disruption, anxiety, and cognitive deficits in chronic immobilization stress-induced rats
by: Mohsen Khodadadi, et al.
Published: (2024-10-01)

Therapeutic effects of crocin in alleviating diabetic neuropathy: a preliminary randomized triple-blind placebo-controlled trial
by: Adeleh Sahebnasagh, et al.
Published: (2025-08-01)

Effects of crocin on brain oxidative damage and aversive memory in a 6-OHDA model of Parkinson’s disease
by: Z Rajaei, et al.

Reversal of anxiety-like depression induced by chronic corticosterone by crocin I and surface-enhanced Raman spectroscopy monitoring of plasma metabolites
by: Dandan Zhang, et al.
Published: (2025-02-01)

CROCIN PROMOTES APOPTOSIS IN HUMAN EBV-TRANSFORMED B-LYMPHOCYTE VIA INTRINSIC PATHWAY
by: Abdolreza Sotoodeh Jahromi, et al.
Published: (2021-06-01)

Comparative assessment of antidepressant-related behaviors of citalopram, crocin, and their combination in non-acute restraint stress and acute restraint stress mice
by: Maryam Parhizkari, et al.
Published: (2025-12-01)

Crocin from saffron ameliorates allergic airway inflammation through NF-κB, IL-17, and Nrf2/HO-1 signaling pathways in mice
by: Farhad Jeddi, et al.
Published: (2024-12-01)

Crocin Alleviates Hippocampal Neuron Injury in Rats with Cerebral Ischemia-Reperfusion by Inhibiting JAK2/STAT3 Signaling Pathway
by: LI Xiaolei, et al.
Published: (2024-06-01)

Characterization of Exosome-like Nanoparticles from Saffron Tepals and Their Immunostimulatory Activity
by: Cristian Martínez Fajardo, et al.
Published: (2025-02-01)

Investigation of the Chemical Compounds, Antioxidant Effect and Therapeutic Properties of Crocus sativus L. (Iridaceae): A Review
by: Huda J. Mhamad, et al.
Published: (2025-02-01)

The impact of phytohormones on the number and quality of flowers in Crocus sativus
by: Jing Chen, et al.
Published: (2025-05-01)

Saffron (Crocus sativus L.): The golden spice — management, challenges, and opportunities for sustainable production in the United States
by: Bharat Sharma Acharya, et al.
Published: (2025-06-01)

Effects of supplementary light treatment on saffron: integrated physiological, metabolomic, and transcriptome analyses
by: Li Li, et al.
Published: (2024-12-01)

The Multifaceted Therapeutic Potential of Saffron: An Overview Based on Research and Patents
by: Yahya Ramadan Elfardi, et al.
Published: (2024-06-01)

FORECASTING OF CCD IN FAMILIES BY MEANS OF A METHOD OF LOGISTIC REGRESSION IN KRASNOYARSK
by: S. Yu. Nikulina, et al.
Published: (2014-10-01)

Reliability and Quality of Complex Systems
by: V.S. Zhabin, et al.
Published: (2025-04-01)

Quantification of apocarotenoids in commercial Indian (Kashmiri) saffron using UV-Vis spectroscopy and HPLC analysis
by: Tahir ul Gani MIR, et al.
Published: (2022-10-01)

EDM-based analysis of Fe-based shape memory alloys using Cu-W electrodes with multiple output optimization and microstructural validation
by: Ranjit Singh, et al.
Published: (2025-08-01)

THE CONTACT PROBLEM STUDY OF THE SELF DUMPING TRUCK DRIVING AXLE HOUSING USING RESPONSE SURFACE METHOD
by: SUN YongGang
Published: (2015-01-01)

Application of the optimized carboxymethylcellulose/green tea/carbon nanotube films/coatings with response surface methodology for the durability extension of red meat: synthesis, antimicrobial and antioxidant properties
by: Mahsa Nazemi, et al.
Published: (2025-12-01)

Genome-wide identification of CCD gene family in Peach (Prunus persica L. Batsch) and expression analysis with aroma norisoprenoids
by: Zhenyu Yao, et al.
Published: (2025-07-01)

Impact of Urban Shrinkage on Pollution Reduction and Carbon Mitigation Synergy: Spatial Heterogeneity and Interaction Effects in Chinese Cities
by: Jianwen Zhang, et al.
Published: (2025-03-01)

Biodiesel production from Sesamum indicum L. seed oil: An optimization study
by: F.A. Dawodu, et al.
Published: (2014-06-01)

Optimization of Process of Dyeing Alpaca Yarn Using Indigo Carmine (C.I. Natural Blue 2)
by: Cristina M. Luque-Jacobo, et al.
Published: (2025-06-01)