Acid-Induced Esophageal Shortening in Humans: A Cause for Hiatus Hernia?
BACKGROUND: Hiatus hernia and gastroesophageal reflux disease commonly coexist, and there is pathophysiological evidence that the presence of a hiatus hernia contributes to abnormal acid reflux. However, the cause of hiatus hernia remains unclear. In an animal model, it has been shown that acute aci...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2000-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2000/438981 |
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| _version_ | 1849415252516536320 |
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| author | Donal P Dunne William G Paterson |
| author_facet | Donal P Dunne William G Paterson |
| author_sort | Donal P Dunne |
| collection | DOAJ |
| description | BACKGROUND: Hiatus hernia and gastroesophageal reflux disease commonly coexist, and there is pathophysiological evidence that the presence of a hiatus hernia contributes to abnormal acid reflux. However, the cause of hiatus hernia remains unclear. In an animal model, it has been shown that acute acid injury to the esophagus results in esophageal shortening, raising the possibility that reflux esophagitis per se can contribute to the formation of hiatus hernia by inducing esophageal shortening. |
| format | Article |
| id | doaj-art-56d76809a71b4dc8af586b47dc13b967 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2000-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-56d76809a71b4dc8af586b47dc13b9672025-08-20T03:33:35ZengWileyCanadian Journal of Gastroenterology0835-79002000-01-01141084785010.1155/2000/438981Acid-Induced Esophageal Shortening in Humans: A Cause for Hiatus Hernia?Donal P Dunne0William G Paterson1GI Diseases Research Unit, Queen’s University, Kingston, Ontario, CanadaGI Diseases Research Unit, Queen’s University, Kingston, Ontario, CanadaBACKGROUND: Hiatus hernia and gastroesophageal reflux disease commonly coexist, and there is pathophysiological evidence that the presence of a hiatus hernia contributes to abnormal acid reflux. However, the cause of hiatus hernia remains unclear. In an animal model, it has been shown that acute acid injury to the esophagus results in esophageal shortening, raising the possibility that reflux esophagitis per se can contribute to the formation of hiatus hernia by inducing esophageal shortening.http://dx.doi.org/10.1155/2000/438981 |
| spellingShingle | Donal P Dunne William G Paterson Acid-Induced Esophageal Shortening in Humans: A Cause for Hiatus Hernia? Canadian Journal of Gastroenterology |
| title | Acid-Induced Esophageal Shortening in Humans: A Cause for Hiatus Hernia? |
| title_full | Acid-Induced Esophageal Shortening in Humans: A Cause for Hiatus Hernia? |
| title_fullStr | Acid-Induced Esophageal Shortening in Humans: A Cause for Hiatus Hernia? |
| title_full_unstemmed | Acid-Induced Esophageal Shortening in Humans: A Cause for Hiatus Hernia? |
| title_short | Acid-Induced Esophageal Shortening in Humans: A Cause for Hiatus Hernia? |
| title_sort | acid induced esophageal shortening in humans a cause for hiatus hernia |
| url | http://dx.doi.org/10.1155/2000/438981 |
| work_keys_str_mv | AT donalpdunne acidinducedesophagealshorteninginhumansacauseforhiatushernia AT williamgpaterson acidinducedesophagealshorteninginhumansacauseforhiatushernia |