ZBTB6 promotes breast cancer progression by inhibiting ARHGAP6 transcription and modulating the STAT3 signaling pathway

ZBTB6 promotes breast cancer progression by inhibiting ARHGAP6 transcription and modulating the STAT3 signaling pathway

Abstract Background The ZBTB (zinc finger and BTB domain-containing) protein family comprises a significant class of transcription factors that interact with various corepressors and histone/protein-modifying enzymes. This interaction facilitates chromatin remodeling and the regulation of gene silen...

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Bibliographic Details
Main Authors: Xiaojiang Tang, Chaowei Deng, Yang Liu, Shengyu Pu, Qi Zheng, Yudong Zhou, Na Hao
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Translational Medicine
Subjects:
ZBTB6
ARHGAP6
Breast cancer
Cell cycle
Apoptosis
STAT3 signaling pathway
Online Access:https://doi.org/10.1186/s12967-025-06364-y
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