Clinical and functional manifestations of hypervolemia in patients with arterial hypertension

Aim. To identify clinical and functional manifestations of hypervolemia in patients with arterial hypertension (AH). Material and methods. In total, 440 patients with Stage I-II AH were examined, including assessment of salt taste sensitivity threshold (STST), 24-hour urinary Na excretion, and NaCl...

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Main Authors: O. B. Poselyugina, S. A. Nilova, V. S. Volkov, Al Galban Hakhed
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2011-04-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/1575
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author O. B. Poselyugina
S. A. Nilova
V. S. Volkov
Al Galban Hakhed
author_facet O. B. Poselyugina
S. A. Nilova
V. S. Volkov
Al Galban Hakhed
author_sort O. B. Poselyugina
collection DOAJ
description Aim. To identify clinical and functional manifestations of hypervolemia in patients with arterial hypertension (AH). Material and methods. In total, 440 patients with Stage I-II AH were examined, including assessment of salt taste sensitivity threshold (STST), 24-hour urinary Na excretion, and NaCl excretion. In addition, 24-hour blood pressure monitoring (BPM), echocardiography (EchoCG), and psychological status assessment (SMOL, MOS SF-36) were performed. Results. In 50,5% of AH patients, daily salt intake (assessed by 24-hour NaCl excretion) was ≥16,8 g, due to adding salt to food, as well as to reduced STST. Higher salt intake was associated with more advanced clinical and functional AH manifestations. Indirect markers of hypervolemia in AH patients included higher salt intake, low effectiveness of standard antihypertensive therapy (AHT), disturbed circadian BP rhythm with inadequate nighttime BP reduction, and EchoCG signs of left ventricular volume overload. Conclusion. Complex examination of AH patients helps to identify individuals with clinical and functional manifestations of hypervolemia.
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institution Kabale University
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publisher «SILICEA-POLIGRAF» LLC
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series Кардиоваскулярная терапия и профилактика
spelling doaj-art-56be993b69b746bbb1da221b33272b4d2025-08-20T03:43:29Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252011-04-01102131710.15829/1728-8800-2011-2-13-171292Clinical and functional manifestations of hypervolemia in patients with arterial hypertensionO. B. Poselyugina0S. A. Nilova1V. S. Volkov2Al Galban Hakhed3Tver State Medical AcademyTver State Medical AcademyTver State Medical AcademyTver State Medical AcademyAim. To identify clinical and functional manifestations of hypervolemia in patients with arterial hypertension (AH). Material and methods. In total, 440 patients with Stage I-II AH were examined, including assessment of salt taste sensitivity threshold (STST), 24-hour urinary Na excretion, and NaCl excretion. In addition, 24-hour blood pressure monitoring (BPM), echocardiography (EchoCG), and psychological status assessment (SMOL, MOS SF-36) were performed. Results. In 50,5% of AH patients, daily salt intake (assessed by 24-hour NaCl excretion) was ≥16,8 g, due to adding salt to food, as well as to reduced STST. Higher salt intake was associated with more advanced clinical and functional AH manifestations. Indirect markers of hypervolemia in AH patients included higher salt intake, low effectiveness of standard antihypertensive therapy (AHT), disturbed circadian BP rhythm with inadequate nighttime BP reduction, and EchoCG signs of left ventricular volume overload. Conclusion. Complex examination of AH patients helps to identify individuals with clinical and functional manifestations of hypervolemia.https://cardiovascular.elpub.ru/jour/article/view/1575arterial hypertensionsalthypervolemia
spellingShingle O. B. Poselyugina
S. A. Nilova
V. S. Volkov
Al Galban Hakhed
Clinical and functional manifestations of hypervolemia in patients with arterial hypertension
Кардиоваскулярная терапия и профилактика
arterial hypertension
salt
hypervolemia
title Clinical and functional manifestations of hypervolemia in patients with arterial hypertension
title_full Clinical and functional manifestations of hypervolemia in patients with arterial hypertension
title_fullStr Clinical and functional manifestations of hypervolemia in patients with arterial hypertension
title_full_unstemmed Clinical and functional manifestations of hypervolemia in patients with arterial hypertension
title_short Clinical and functional manifestations of hypervolemia in patients with arterial hypertension
title_sort clinical and functional manifestations of hypervolemia in patients with arterial hypertension
topic arterial hypertension
salt
hypervolemia
url https://cardiovascular.elpub.ru/jour/article/view/1575
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AT sanilova clinicalandfunctionalmanifestationsofhypervolemiainpatientswitharterialhypertension
AT vsvolkov clinicalandfunctionalmanifestationsofhypervolemiainpatientswitharterialhypertension
AT algalbanhakhed clinicalandfunctionalmanifestationsofhypervolemiainpatientswitharterialhypertension