RS3PE: A Rheumatic Presentation of Lung Malignancy
We describe a previously well 56-year-old man who presented with symmetrical inflammatory polyarthralgia associated with bilateral lower limb swelling and left hand puffiness. He had noticed blood steaks in his productive cough for half a year but reported no constitutional symptoms. Inflammatory ma...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2023-07-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2022.0983 |
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| _version_ | 1850197889102381056 |
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| author | Chester Yan Hao Ng Chrystie Wan Ning Quek Yi Ting Lim Jiacai Cho |
| author_facet | Chester Yan Hao Ng Chrystie Wan Ning Quek Yi Ting Lim Jiacai Cho |
| author_sort | Chester Yan Hao Ng |
| collection | DOAJ |
| description | We describe a previously well 56-year-old man who presented with symmetrical inflammatory polyarthralgia associated with bilateral lower limb swelling and left hand puffiness. He had noticed blood steaks in his productive cough for half a year but reported no constitutional symptoms. Inflammatory markers were elevated, whereas rheumatoid factor was negative. Imaging of the chest showed a mass in the right upper zone, which was confirmed via biopsy to be ALK-positive lung adenocarcinoma. The patient was diagnosed with paraneoplastic remitting seronegative symmetrical synovitis with pitting edema, representing one of the first descriptions of lung adenocarcinoma–associated RS3PE. |
| format | Article |
| id | doaj-art-56bc04cfc15642e5bd4bf349087b9d27 |
| institution | OA Journals |
| issn | 2767-7664 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-56bc04cfc15642e5bd4bf349087b9d272025-08-20T02:13:01ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642023-07-012710.7326/aimcc.2022.0983RS3PE: A Rheumatic Presentation of Lung MalignancyChester Yan Hao Ng0Chrystie Wan Ning Quek1Yi Ting Lim2Jiacai Cho31Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore1Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore2Department of Diagnostic Imaging, National University Hospital, Singapore1Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, SingaporeWe describe a previously well 56-year-old man who presented with symmetrical inflammatory polyarthralgia associated with bilateral lower limb swelling and left hand puffiness. He had noticed blood steaks in his productive cough for half a year but reported no constitutional symptoms. Inflammatory markers were elevated, whereas rheumatoid factor was negative. Imaging of the chest showed a mass in the right upper zone, which was confirmed via biopsy to be ALK-positive lung adenocarcinoma. The patient was diagnosed with paraneoplastic remitting seronegative symmetrical synovitis with pitting edema, representing one of the first descriptions of lung adenocarcinoma–associated RS3PE.https://www.acpjournals.org/doi/10.7326/aimcc.2022.0983 |
| spellingShingle | Chester Yan Hao Ng Chrystie Wan Ning Quek Yi Ting Lim Jiacai Cho RS3PE: A Rheumatic Presentation of Lung Malignancy Annals of Internal Medicine: Clinical Cases |
| title | RS3PE: A Rheumatic Presentation of Lung Malignancy |
| title_full | RS3PE: A Rheumatic Presentation of Lung Malignancy |
| title_fullStr | RS3PE: A Rheumatic Presentation of Lung Malignancy |
| title_full_unstemmed | RS3PE: A Rheumatic Presentation of Lung Malignancy |
| title_short | RS3PE: A Rheumatic Presentation of Lung Malignancy |
| title_sort | rs3pe a rheumatic presentation of lung malignancy |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2022.0983 |
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