The association of FAT1 mutations with therapeutic outcomes in AML, especially in receiving venetoclax combination

The association of FAT1 mutations with therapeutic outcomes in AML, especially in receiving venetoclax combination

ObjectiveThe role of FAT1 mutations in acute myeloid leukemia (AML) remains unclear, particularly regarding their impact on the chemosensitivity of AML patients. To elucidate the effect of FAT1 mutations on the therapeutic outcomes and prognosis of AML patients, we conducted this study.MethodsTo ana...

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Bibliographic Details
Main Authors: Tao Wang, Junxia Huang, Yongqian Jia, Junting Li, Weiwei Mou, Guang Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Oncology
Subjects:
AML
FAT1
venetoclax (ABT-199)
mutation
therapeutic outcome
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1456832/full
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