Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case report

Simultaneous presentation of tuberculosis (TB) and lymphoma in a young child is indeed a very rare entity. Malignancy such as Hodgkin's disease (HD) most commonly causes suppression of the cell-mediated immunity, which makes the individual, especially children, more prone to tuberculous infecti...

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Main Authors: A. Juneja, MDS, MA (Psychology), A. Sultan, MDS, S. Iqbal
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Journal of Oral Biology and Craniofacial Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221242682030035X
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author A. Juneja, MDS, MA (Psychology)
A. Sultan, MDS
S. Iqbal
author_facet A. Juneja, MDS, MA (Psychology)
A. Sultan, MDS
S. Iqbal
author_sort A. Juneja, MDS, MA (Psychology)
collection DOAJ
description Simultaneous presentation of tuberculosis (TB) and lymphoma in a young child is indeed a very rare entity. Malignancy such as Hodgkin's disease (HD) most commonly causes suppression of the cell-mediated immunity, which makes the individual, especially children, more prone to tuberculous infection. One of the non-life threatening complications in these young cancer survivors is the associated dental anomalies. These can seriously impair the quality of life of teenagers and young adults. Higher incidence of caries, discoloration of teeth or even early loss of teeth requiring dental prosthesis, can be associated with the use of cytostatic drugs. These drugs can also disturb odontogenesis, resulting in the absence of tooth buds, microdontia, dilacerations or shortening of tooth roots. Some of the anticancer drugs, including busulfan, cyclophosphamide, doxorubicin etc. May particularly play a significant role in the development of dental anomalies.This paper is a short review and case report of an 11 year old child having oligodontia and secondary dental complications caused as a side effect of treatment of Hodgkin's lymphoma with Tuberculous Lymphadenitis.
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spelling doaj-art-5696d762bd6a46c684ec46153cb89def2025-08-20T02:50:27ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682020-04-0110213513710.1016/j.jobcr.2020.04.002Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case reportA. Juneja, MDS, MA (Psychology)0A. Sultan, MDS1S. Iqbal2Dept of Pediatric and Preventive Dentistry, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India; Corresponding author. Dept Of Pediatric and Preventive Dentistry, Faculty of Dentistry, Jamia Millia Islamia, New Delhi. Ph no: 9971404330.Dept of Pediatric and Preventive Dentistry, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, IndiaFaculty of Dentistry, Jamia Millia Islamia, New Delhi, IndiaSimultaneous presentation of tuberculosis (TB) and lymphoma in a young child is indeed a very rare entity. Malignancy such as Hodgkin's disease (HD) most commonly causes suppression of the cell-mediated immunity, which makes the individual, especially children, more prone to tuberculous infection. One of the non-life threatening complications in these young cancer survivors is the associated dental anomalies. These can seriously impair the quality of life of teenagers and young adults. Higher incidence of caries, discoloration of teeth or even early loss of teeth requiring dental prosthesis, can be associated with the use of cytostatic drugs. These drugs can also disturb odontogenesis, resulting in the absence of tooth buds, microdontia, dilacerations or shortening of tooth roots. Some of the anticancer drugs, including busulfan, cyclophosphamide, doxorubicin etc. May particularly play a significant role in the development of dental anomalies.This paper is a short review and case report of an 11 year old child having oligodontia and secondary dental complications caused as a side effect of treatment of Hodgkin's lymphoma with Tuberculous Lymphadenitis.http://www.sciencedirect.com/science/article/pii/S221242682030035XAnomaliesHodgkins lymphomaTuberculousDrugsTooth agenesis
spellingShingle A. Juneja, MDS, MA (Psychology)
A. Sultan, MDS
S. Iqbal
Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case report
Journal of Oral Biology and Craniofacial Research
Anomalies
Hodgkins lymphoma
Tuberculous
Drugs
Tooth agenesis
title Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case report
title_full Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case report
title_fullStr Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case report
title_full_unstemmed Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case report
title_short Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case report
title_sort exploring the presence of dental anomalies as a consequence of treatment of malignancy a case report
topic Anomalies
Hodgkins lymphoma
Tuberculous
Drugs
Tooth agenesis
url http://www.sciencedirect.com/science/article/pii/S221242682030035X
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AT siqbal exploringthepresenceofdentalanomaliesasaconsequenceoftreatmentofmalignancyacasereport