Regenerative Capacity of Alveolar Type 2 Cells Is Proportionally Reduced Following Disease Progression in Idiopathic Pulmonary Fibrosis-Derived Organoid Cultures

Regenerative Capacity of Alveolar Type 2 Cells Is Proportionally Reduced Following Disease Progression in Idiopathic Pulmonary Fibrosis-Derived Organoid Cultures

Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease that culminates in respiratory failure and death due to irreversible scarring of the distal lung. While initially considered a chronic inflammatory disorder, the aberrant function of the alveolar epithelium is now...

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Main Authors: Hyeon Kyu Choi, Gaeul Bang, Ju Hye Shin, Mi Hwa Shin, Ala Woo, Song Yee Kim, Sang Hoon Lee, Eun Young Kim, Hyo Sup Shim, Young Joo Suh, Ha Eun Kim, Jin Gu Lee, Jinwook Choi, Ju Hyeon Lee, Chul Hoon Kim, Moo Suk Park
Format: Article
Language:English
Published: The Korean Academy of Tuberculosis and Respiratory Diseases 2025-01-01
Series:Tuberculosis and Respiratory Diseases
Subjects:
idiopathic pulomonary fibrosis
alveolar type 2 cells
patient-derived lung organoid
lung regeneration
Online Access:http://e-trd.org/upload/pdf/trd-2024-0094.pdf
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