Chronic Neutrophilic Meningitis in Tuberculous Infection: A Rare Case Presentation and review of the literature

Persistent neutrophilic pleocytosis syndrome is a rare form of tuberculous meningitis that is defined as the persistence of neutrophils in cerebrospinal fluid for more than 7 days, in association with the clinical features of meningitis (headache, fever, and positive meningeal signs).1 The exact pat...

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Main Authors: Amanj Jamal Pastaksor, Ahmed Kawa Fathi
Format: Article
Language:English
Published: Kurdistan Higher Council Of Medical Specialties 2024-12-01
Series:Advanced Medical Journal
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Online Access:https://amj.khcms.edu.krd/index.php/main/article/view/543
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author Amanj Jamal Pastaksor
Ahmed Kawa Fathi
author_facet Amanj Jamal Pastaksor
Ahmed Kawa Fathi
author_sort Amanj Jamal Pastaksor
collection DOAJ
description Persistent neutrophilic pleocytosis syndrome is a rare form of tuberculous meningitis that is defined as the persistence of neutrophils in cerebrospinal fluid for more than 7 days, in association with the clinical features of meningitis (headache, fever, and positive meningeal signs).1 The exact pathogenesis of this syndrome is not well known yet, and it has many diverse etiologies, including infectious and noninfectious ones. among infectious ones: bacteria such as Nocardia and Actinomyces, and systemic mycoses such as Aspergillus and the zygomycetes, as well as mycobacterium.2 This entity is very rare in immunocompetent patients, and most of the cases are due to infectious causes in those who are immunocompromised. The usual scenario in such cases is initiating broad-spectrum antimicrobial agents without any improvement, therefore the diagnosis is difficult initially and often delayed. Therefore, the epidemiologic features and clinical profile may offer clues to the etiologic agent, especially in the immunocompromised host.3
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publishDate 2024-12-01
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spelling doaj-art-56760c227b5a49fea6071bd993f1c8ae2025-08-20T03:18:46ZengKurdistan Higher Council Of Medical SpecialtiesAdvanced Medical Journal2958-89792957-35802024-12-019410.56056/amj.2024.310544Chronic Neutrophilic Meningitis in Tuberculous Infection: A Rare Case Presentation and review of the literatureAmanj Jamal Pastaksor0Ahmed Kawa Fathi1M.B.Ch.B, F.I.B.M.S Neurology , Fellow Of Iraqi Board Of Medical Specialties(neurology),DIM, senior neurologist, Erbil Teaching Hospital –Erbil-Kurdistan region/IraqM.B.Ch.B ,F.K.H.C.M.S(neurology) Fellow of Kurdistan higher council of Medical Specialties/Clinical neurology, -Erbil - Kurdistan region/IraqPersistent neutrophilic pleocytosis syndrome is a rare form of tuberculous meningitis that is defined as the persistence of neutrophils in cerebrospinal fluid for more than 7 days, in association with the clinical features of meningitis (headache, fever, and positive meningeal signs).1 The exact pathogenesis of this syndrome is not well known yet, and it has many diverse etiologies, including infectious and noninfectious ones. among infectious ones: bacteria such as Nocardia and Actinomyces, and systemic mycoses such as Aspergillus and the zygomycetes, as well as mycobacterium.2 This entity is very rare in immunocompetent patients, and most of the cases are due to infectious causes in those who are immunocompromised. The usual scenario in such cases is initiating broad-spectrum antimicrobial agents without any improvement, therefore the diagnosis is difficult initially and often delayed. Therefore, the epidemiologic features and clinical profile may offer clues to the etiologic agent, especially in the immunocompromised host.3 https://amj.khcms.edu.krd/index.php/main/article/view/543MeningitisTuberculous Infection
spellingShingle Amanj Jamal Pastaksor
Ahmed Kawa Fathi
Chronic Neutrophilic Meningitis in Tuberculous Infection: A Rare Case Presentation and review of the literature
Advanced Medical Journal
Meningitis
Tuberculous Infection
title Chronic Neutrophilic Meningitis in Tuberculous Infection: A Rare Case Presentation and review of the literature
title_full Chronic Neutrophilic Meningitis in Tuberculous Infection: A Rare Case Presentation and review of the literature
title_fullStr Chronic Neutrophilic Meningitis in Tuberculous Infection: A Rare Case Presentation and review of the literature
title_full_unstemmed Chronic Neutrophilic Meningitis in Tuberculous Infection: A Rare Case Presentation and review of the literature
title_short Chronic Neutrophilic Meningitis in Tuberculous Infection: A Rare Case Presentation and review of the literature
title_sort chronic neutrophilic meningitis in tuberculous infection a rare case presentation and review of the literature
topic Meningitis
Tuberculous Infection
url https://amj.khcms.edu.krd/index.php/main/article/view/543
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