Metagenomic analysis of human, animal, and environmental samples identifies potential emerging pathogens, profiles antibiotic resistance genes, and reveals horizontal gene transfer dynamics

Metagenomic analysis of human, animal, and environmental samples identifies potential emerging pathogens, profiles antibiotic resistance genes, and reveals horizontal gene transfer dynamics

Abstract Antimicrobial resistance (AMR) poses a significant threat to global health. The indiscriminate use of antibiotics has accelerated the emergence and spread of drug-resistant bacteria, compromising our ability to treat infectious diseases. A One Health approach is essential to address this ur...

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Bibliographic Details
Main Authors: Rajindra Napit, Anupama Gurung, Ajit Poudel, Ashok Chaudhary, Prajwol Manandhar, Ajay Narayan Sharma, Samita Raut, Saman Man Pradhan, Jyotsna Joshi, Mathilde Poyet, Mathieu Groussin, Rajesh M. Rajbhandari, Dibesh B. Karmacharya
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Antimicrobial resistance
Antimicrobial resistance genes
Gut microbiome
Horizontal gene transfer
One health
Online Access:https://doi.org/10.1038/s41598-025-90777-8
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