Ethanolic Extract of Red Okra Pods Induces Aberrant Spindle Segregation and Apoptotic Cell Death by Disrupting the Wnt Signaling Pathway in Colon Cancer Cells

Ethanolic Extract of Red Okra Pods Induces Aberrant Spindle Segregation and Apoptotic Cell Death by Disrupting the Wnt Signaling Pathway in Colon Cancer Cells

Background: In approximately 80% of colorectal cancer cases, mutations in the adenomatous polyposis coli (APC) gene disrupt the Wingless-related integration site (Wnt)/β-catenin signaling pathway, a crucial factor in carcinogenesis. This disruption may result in consequences such as aberrant spindle...

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Bibliographic Details
Main Authors: Firli Rahmah Primula Dewi, Sri Puji Astuti Wahyuningsih, Vuanghao Lim, Lionel Lian Aun In, Alfiah Hayati
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2024-12-01
Series:Iranian Journal of Medical Sciences
Subjects:
abelmoschus esculentus
apoptosis
colorectal cancer
wnt signaling pathway
Online Access:https://ijms.sums.ac.ir/article_50163_fbfb480803b7c878fa6583062f35a3d2.pdf
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