Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo.

Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo.

The precise context in which the innate immune system is activated plays a pivotal role in the subsequent instruction of CD4+ T helper (Th) cell responses. Th1 responses are downregulated when antigen is encountered in the presence of antigen-IgG immune complexes. To assess if Th17 responses to anti...

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Main Authors: Ceren Ciraci, John R Janczy, Nidhi Jain, Stefanie Haasken, Cyntia Pecli E Silva, Claudia F Benjamim, Jeffrey J Sadler, Alicia K Olivier, Yoichiro Iwakura, Dmitry M Shayakhmetov, Fayyaz S Sutterwala, Suzanne L Cassel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0151252&type=printable
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