Dynamic functional MRI markers of drowsiness during sleep onset period

Summary: The present use of ocular activity to enhance the temporal resolution of the classification of sleep onset period (SOP) allowed to reveal an increase in the power of oscillations in the BOLD signal at 0.05 Hz in the brain, particularly in sensory cortices, as soon as the first signs of drow...

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Main Authors: Ivan Igor Gaez, Elpidio Attoh-Mensah, Clément Nathou, Lydie Vincent, Marc Joliot, Luc Brun, Mikaël Naveau, Olivier Etard
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225013495
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author Ivan Igor Gaez
Elpidio Attoh-Mensah
Clément Nathou
Lydie Vincent
Marc Joliot
Luc Brun
Mikaël Naveau
Olivier Etard
author_facet Ivan Igor Gaez
Elpidio Attoh-Mensah
Clément Nathou
Lydie Vincent
Marc Joliot
Luc Brun
Mikaël Naveau
Olivier Etard
author_sort Ivan Igor Gaez
collection DOAJ
description Summary: The present use of ocular activity to enhance the temporal resolution of the classification of sleep onset period (SOP) allowed to reveal an increase in the power of oscillations in the BOLD signal at 0.05 Hz in the brain, particularly in sensory cortices, as soon as the first signs of drowsiness. These changes were evident in the “likely drowsy” state of SOP, representing early sleep-related vigilance fluctuations, often encountered even during activities like driving. Our findings show changes in the BOLD signal even before conventional indicators of sleep onset.
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publishDate 2025-08-01
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spelling doaj-art-565377da92754fe68f8ffc53ee85e95e2025-08-20T02:47:13ZengElsevieriScience2589-00422025-08-0128811308810.1016/j.isci.2025.113088Dynamic functional MRI markers of drowsiness during sleep onset periodIvan Igor Gaez0Elpidio Attoh-Mensah1Clément Nathou2Lydie Vincent3Marc Joliot4Luc Brun5Mikaël Naveau6Olivier Etard7Normandie Université, UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Caen, FranceUniversité de Limoges, HAVAE, UR 20217, 87000 Limoges, France; Corresponding authorNormandie Université, UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Caen, FranceNormandie Université, UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Caen, FranceGIN, UMR5293, CEA, CNRS, Université de Bordeaux, Bordeaux, FranceNormandie Université, UNICAEN, ENSICAEN, CNRS, GREYC, 14000 Caen, FranceNormandie Université, UNICAEN, CNRS, UMS3408 CYCERON, Caen, FranceNormandie Université, UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Caen, France; Corresponding authorSummary: The present use of ocular activity to enhance the temporal resolution of the classification of sleep onset period (SOP) allowed to reveal an increase in the power of oscillations in the BOLD signal at 0.05 Hz in the brain, particularly in sensory cortices, as soon as the first signs of drowsiness. These changes were evident in the “likely drowsy” state of SOP, representing early sleep-related vigilance fluctuations, often encountered even during activities like driving. Our findings show changes in the BOLD signal even before conventional indicators of sleep onset.http://www.sciencedirect.com/science/article/pii/S2589004225013495Health sciencesNeuroscience
spellingShingle Ivan Igor Gaez
Elpidio Attoh-Mensah
Clément Nathou
Lydie Vincent
Marc Joliot
Luc Brun
Mikaël Naveau
Olivier Etard
Dynamic functional MRI markers of drowsiness during sleep onset period
iScience
Health sciences
Neuroscience
title Dynamic functional MRI markers of drowsiness during sleep onset period
title_full Dynamic functional MRI markers of drowsiness during sleep onset period
title_fullStr Dynamic functional MRI markers of drowsiness during sleep onset period
title_full_unstemmed Dynamic functional MRI markers of drowsiness during sleep onset period
title_short Dynamic functional MRI markers of drowsiness during sleep onset period
title_sort dynamic functional mri markers of drowsiness during sleep onset period
topic Health sciences
Neuroscience
url http://www.sciencedirect.com/science/article/pii/S2589004225013495
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