Optimization for the production of a dengue live-attenuated Quadrivalent vaccine in Vero cells grown on microcarriers

Optimization for the production of a dengue live-attenuated Quadrivalent vaccine in Vero cells grown on microcarriers

Dengue is a mosquito-borne disease and is a major global health threat, especially in tropical and subtropical regions. In this study, we describe the optimization of virus production for a dengue live-attenuated quadrivalent vaccine candidate and demonstrate scalability of a stirred tank bioreactor...

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Bibliographic Details
Main Authors: Shannon Haughney, Seth Clark, Elizabeth Carey, Nelson Lee Afanador, Victoria Stabile, Bernard Kang, Samantha Marrone, Jillian Shingler, Carl Hofmann, Christopher J. Wang, Christopher Ton
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Vaccine: X
Online Access:http://www.sciencedirect.com/science/article/pii/S259013622500052X
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