Computational fluid dynamic analysis in infrarenal abdominal aortic aneurysm for surveillance of aneurysm potential rupture
Objective: This study aims to identify the morphology of infrarenal abdominal aortic aneurysms (AAAs) and analyze wall shear stress (WSS) and wall pressure (WP) using computational fluid dynamic analysis to predict potential rupture areas. Methods: A cross-sectional study was conducted on patients w...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | JVS-Vascular Insights |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949912725000844 |
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| author | Nyityasmono Tri Nugroho, MD, PhD Agus Prasetyo Nuryadi, BEng Muhammad Ilyas, MD Muhammad Hanif Nadhif, BEng Reyhan Eddy Yunus, MD Raden Suhartono, MD, PhD |
| author_facet | Nyityasmono Tri Nugroho, MD, PhD Agus Prasetyo Nuryadi, BEng Muhammad Ilyas, MD Muhammad Hanif Nadhif, BEng Reyhan Eddy Yunus, MD Raden Suhartono, MD, PhD |
| author_sort | Nyityasmono Tri Nugroho, MD, PhD |
| collection | DOAJ |
| description | Objective: This study aims to identify the morphology of infrarenal abdominal aortic aneurysms (AAAs) and analyze wall shear stress (WSS) and wall pressure (WP) using computational fluid dynamic analysis to predict potential rupture areas. Methods: A cross-sectional study was conducted on patients with infrarenal AAAs at the Vascular and Endovascular Division, Department of Surgery, and the Department of Radiology, RSUPN Dr Cipto Mangunkusumo, from July to December 2022. Three-dimensional models were reconstructed from computed tomography angiograms, and infrarenal AAAs were classified into five morphologic types. Computational fluid dynamic analysis was performed to generate WSS and WP contours at varying blood pressure and velocity. Visual results for each type were analyzed and compared. Statistical analysis was conducted using SPSS 25.0. Results: From 93 computed tomography angiograms, 40 samples met the inclusion criteria. Twenty-five percent of samples had a saccular component. Visual analysis showed a correlation between areas of lowest WSS and highest WP. Velocity and blood pressure also affected WSS and WP; however, the center of the contour as potential prediction rupture sites remained consistent. Significant differences were found in WSS and WP (P = .038 and P < .001, respectively). Conclusions: Areas of lowest WSS correspond with highest WP, indicating potential rupture sites. Blood velocity and pressure changes also influenced WSS and WP. Surveillance should be subjected to closer inspection on the areas with the lowest WSS. |
| format | Article |
| id | doaj-art-563cc0108c644cea9d7ea0ff2cd539ff |
| institution | Kabale University |
| issn | 2949-9127 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
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| series | JVS-Vascular Insights |
| spelling | doaj-art-563cc0108c644cea9d7ea0ff2cd539ff2025-08-20T05:08:32ZengElsevierJVS-Vascular Insights2949-91272025-01-01310026710.1016/j.jvsvi.2025.100267Computational fluid dynamic analysis in infrarenal abdominal aortic aneurysm for surveillance of aneurysm potential ruptureNyityasmono Tri Nugroho, MD, PhD0Agus Prasetyo Nuryadi, BEng1Muhammad Ilyas, MD2Muhammad Hanif Nadhif, BEng3Reyhan Eddy Yunus, MD4Raden Suhartono, MD, PhD5Division of Vascular and Endovascular, Department of Surgery, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Centre General Hospital, Jakarta, Indonesia; Correspondence: Nyityasmono Tri Nugroho, MD, PhD, Division of Vascular and Endovascular, Department of Surgery, Hospital Dr. Cipto Mangunkusumo, Bldg A, Third Fl, Jl. Diponegoro 71, Jakarta 10430, IndonesiaNational Agency for Research and Innovation - Center for Energy Conversion and Conservation, Jakarta, IndonesiaNational Agency for Research and Innovation - Center for Energy Conversion and Conservation, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jakarta, IndonesiaDivision of Vascular and Endovascular, Department of Surgery, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Centre General Hospital, Jakarta, Indonesia; Department of Surgery, Faculty of Medicine Universitas Indonesia - Universitas Indonesia Hospital, Depok, Indonesia; National Agency for Research and Innovation - Center for Energy Conversion and Conservation, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Medical Physiology and Biophysics, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine, University of Indonesia, Hospital Dr. Cipto Mangunkusumo, Jakarta, IndonesiaDivision of Vascular and Endovascular, Department of Surgery, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Centre General Hospital, Jakarta, Indonesia; Department of Surgery, Faculty of Medicine Universitas Indonesia - Universitas Indonesia Hospital, Depok, Indonesia; National Agency for Research and Innovation - Center for Energy Conversion and Conservation, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Medical Physiology and Biophysics, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine, University of Indonesia, Hospital Dr. Cipto Mangunkusumo, Jakarta, IndonesiaDivision of Vascular and Endovascular, Department of Surgery, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Centre General Hospital, Jakarta, IndonesiaObjective: This study aims to identify the morphology of infrarenal abdominal aortic aneurysms (AAAs) and analyze wall shear stress (WSS) and wall pressure (WP) using computational fluid dynamic analysis to predict potential rupture areas. Methods: A cross-sectional study was conducted on patients with infrarenal AAAs at the Vascular and Endovascular Division, Department of Surgery, and the Department of Radiology, RSUPN Dr Cipto Mangunkusumo, from July to December 2022. Three-dimensional models were reconstructed from computed tomography angiograms, and infrarenal AAAs were classified into five morphologic types. Computational fluid dynamic analysis was performed to generate WSS and WP contours at varying blood pressure and velocity. Visual results for each type were analyzed and compared. Statistical analysis was conducted using SPSS 25.0. Results: From 93 computed tomography angiograms, 40 samples met the inclusion criteria. Twenty-five percent of samples had a saccular component. Visual analysis showed a correlation between areas of lowest WSS and highest WP. Velocity and blood pressure also affected WSS and WP; however, the center of the contour as potential prediction rupture sites remained consistent. Significant differences were found in WSS and WP (P = .038 and P < .001, respectively). Conclusions: Areas of lowest WSS correspond with highest WP, indicating potential rupture sites. Blood velocity and pressure changes also influenced WSS and WP. Surveillance should be subjected to closer inspection on the areas with the lowest WSS.http://www.sciencedirect.com/science/article/pii/S2949912725000844Abdominal aortic aneurysmAneurysm ruptureComputational fluid dynamicsWall pressureWall shear stress |
| spellingShingle | Nyityasmono Tri Nugroho, MD, PhD Agus Prasetyo Nuryadi, BEng Muhammad Ilyas, MD Muhammad Hanif Nadhif, BEng Reyhan Eddy Yunus, MD Raden Suhartono, MD, PhD Computational fluid dynamic analysis in infrarenal abdominal aortic aneurysm for surveillance of aneurysm potential rupture JVS-Vascular Insights Abdominal aortic aneurysm Aneurysm rupture Computational fluid dynamics Wall pressure Wall shear stress |
| title | Computational fluid dynamic analysis in infrarenal abdominal aortic aneurysm for surveillance of aneurysm potential rupture |
| title_full | Computational fluid dynamic analysis in infrarenal abdominal aortic aneurysm for surveillance of aneurysm potential rupture |
| title_fullStr | Computational fluid dynamic analysis in infrarenal abdominal aortic aneurysm for surveillance of aneurysm potential rupture |
| title_full_unstemmed | Computational fluid dynamic analysis in infrarenal abdominal aortic aneurysm for surveillance of aneurysm potential rupture |
| title_short | Computational fluid dynamic analysis in infrarenal abdominal aortic aneurysm for surveillance of aneurysm potential rupture |
| title_sort | computational fluid dynamic analysis in infrarenal abdominal aortic aneurysm for surveillance of aneurysm potential rupture |
| topic | Abdominal aortic aneurysm Aneurysm rupture Computational fluid dynamics Wall pressure Wall shear stress |
| url | http://www.sciencedirect.com/science/article/pii/S2949912725000844 |
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