Inference of antimicrobial resistance (AMR) from a whole genome database outperforming AMR gene detection

Inference of antimicrobial resistance (AMR) from a whole genome database outperforming AMR gene detection

Summary: This study focuses on the rapid detection of antimicrobial resistance (AMR) in Klebsiella pneumoniae. The “Align-Search-Infer” pipeline aligned query sequences from 24 urine samples against a curated genome database of 40 Klebsiella isolates, searched for the best matches, and inferred thei...

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Main Authors: Pornsawan Cholsaktrakool, Kornthara Kawang, Nicha Sangpiromapichai, Pannaporn Thongsuk, Songtham Anuntakarun, Pattapon Kunadirek, Natthaya Chuaypen, Sumanee Nilgate, Naris Kueakulpattana, Ubolrat Rirerm, Tanittha Chatsuwan, Elita Jauneikaite, Frances Davies, Ploy N. Pratanwanich, Sira Sriswasdi, Voraphoj Nilaratanakul
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
Subjects:
Natural sciences
Biological sciences
Microbiology
Microbial genomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225012234
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