Effectiveness and safety of nivolumab and ipilimumab in older adults with renal cell carcinoma: findings from a multicenter observational study in Poland

Effectiveness and safety of nivolumab and ipilimumab in older adults with renal cell carcinoma: findings from a multicenter observational study in Poland

BackgroundNivolumab and ipilimumab (nivo+ipi) are recommended for treating metastatic clear cell renal cell carcinoma (mRCC), though their safety and efficacy in older adults remain uncertain. This study examines the outcomes of this regimen in Polish patients aged ≥65 years.MethodsIn this multicent...

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Main Authors: Artur Drobniak, Łukasz Stokłosa, Aleksandra Grela-Wojewoda, Jacek Calik, Natalia Versuti Viegas, Jolanta Dobrzańska, Agnieszka Roman, Marek Szwiec, Anna Bidas, Daria Tusień-Małecka, Angelika Gawlik-Urban, Mirosława Puskulluoglu, Renata Pacholczak-Madej
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
renal cell carcinoma
nivolumab and ipilimumab
immune checkpoint inhibitors
elderly
treatment outcome
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1617743/full
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