Quantification of a potential anticonvulsant drug GIZh-298 in rat plasma by liquid chromatography-mass spectrometry

GIZh-298 is a new derivative of 4-phenylpyrrolidone with anticonvulsant and nootropic effects. A selective and sensitive HPLC-MS technique for the quantitative determination of GIZh-298 in rat blood plasma has been developed and validated. The linearity of the technique was confirmed by a high corre...

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Bibliographic Details
Main Authors: P. O. Bochkov, O. Yu. Kravtsova, G. B. Kolyvanov, A. A. Litvin, S. S. Boyko, V. P. Zherdev
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2022-12-01
Series:Фармакокинетика и Фармакодинамика
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Online Access:https://www.pharmacokinetica.ru/jour/article/view/331
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