Immune response, smoking, and lung cancer: a systematic review
Here we review the role of innate and adaptive immunity at ascending lung cancer stages in smoking and non-smoking patients. T cell activity and the expression of pro-inflammatory cytokines were found to be elevated in smokers. As a consequence, smoking has been identified as a significant risk fact...
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| Format: | Article |
| Language: | Russian |
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Kemerovo State Medical University
2024-09-01
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| Series: | Фундаментальная и клиническая медицина |
| Subjects: | |
| Online Access: | https://fcm.kemsmu.ru/jour/article/view/904 |
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| _version_ | 1849697565691346944 |
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| author | V. Yu. Buslaev A. V. Minin M. V. Katanakhova A. V. Shabaldin |
| author_facet | V. Yu. Buslaev A. V. Minin M. V. Katanakhova A. V. Shabaldin |
| author_sort | V. Yu. Buslaev |
| collection | DOAJ |
| description | Here we review the role of innate and adaptive immunity at ascending lung cancer stages in smoking and non-smoking patients. T cell activity and the expression of pro-inflammatory cytokines were found to be elevated in smokers. As a consequence, smoking has been identified as a significant risk factor promoting lung carcinogenesis. Further experimental research in this area will allow the development of novel diagnostic approaches, including circulating biomarkers and personalised medicine. |
| format | Article |
| id | doaj-art-562abd50b9804662bfb2ca6ac47674d4 |
| institution | DOAJ |
| issn | 2500-0764 2542-0941 |
| language | Russian |
| publishDate | 2024-09-01 |
| publisher | Kemerovo State Medical University |
| record_format | Article |
| series | Фундаментальная и клиническая медицина |
| spelling | doaj-art-562abd50b9804662bfb2ca6ac47674d42025-08-20T03:19:11ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412024-09-0193869710.23946/2500-0764-2024-9-3-86-97443Immune response, smoking, and lung cancer: a systematic reviewV. Yu. Buslaev0A. V. Minin1M. V. Katanakhova2A. V. Shabaldin3Institute of Human Ecology, Federal Research Center of Coal and Coal Chemistry of Siberian Branch of the Russian Academy of SciencesInstitute of Human Ecology, Federal Research Center of Coal and Coal Chemistry of Siberian Branch of the Russian Academy of Sciences; Kemerovo State UniversityInstitute of Human Ecology, Federal Research Center of Coal and Coal Chemistry of Siberian Branch of the Russian Academy of Sciences; Kemerovo State UniversityKemerovo State University; Kemerovo State Medical UniversityHere we review the role of innate and adaptive immunity at ascending lung cancer stages in smoking and non-smoking patients. T cell activity and the expression of pro-inflammatory cytokines were found to be elevated in smokers. As a consequence, smoking has been identified as a significant risk factor promoting lung carcinogenesis. Further experimental research in this area will allow the development of novel diagnostic approaches, including circulating biomarkers and personalised medicine.https://fcm.kemsmu.ru/jour/article/view/904reviewsmokingimmunity factorslung cancer |
| spellingShingle | V. Yu. Buslaev A. V. Minin M. V. Katanakhova A. V. Shabaldin Immune response, smoking, and lung cancer: a systematic review Фундаментальная и клиническая медицина review smoking immunity factors lung cancer |
| title | Immune response, smoking, and lung cancer: a systematic review |
| title_full | Immune response, smoking, and lung cancer: a systematic review |
| title_fullStr | Immune response, smoking, and lung cancer: a systematic review |
| title_full_unstemmed | Immune response, smoking, and lung cancer: a systematic review |
| title_short | Immune response, smoking, and lung cancer: a systematic review |
| title_sort | immune response smoking and lung cancer a systematic review |
| topic | review smoking immunity factors lung cancer |
| url | https://fcm.kemsmu.ru/jour/article/view/904 |
| work_keys_str_mv | AT vyubuslaev immuneresponsesmokingandlungcancerasystematicreview AT avminin immuneresponsesmokingandlungcancerasystematicreview AT mvkatanakhova immuneresponsesmokingandlungcancerasystematicreview AT avshabaldin immuneresponsesmokingandlungcancerasystematicreview |